Short Description

NGS genetic DNA test detecets for variant and mutation detection in ZDHHC15 gene for Mental retardation, X-linked type 91

PreTest Information

Clinical History of Patient who is going for ZDHHC15 Gene Mental retardation, X-linked type 91 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with ZDHHC15 Gene Mental retardation, X-linked type 91

Detail Description

ZDHHC15 Gene Mental Retardation, X-linked Type 91 NGS Genetic DNA Test

Genetic disorders are caused by changes or mutations in genes, which are the basic units of heredity. One such genetic disorder is X-linked mental retardation, which affects only males and is caused by mutations in genes on the X chromosome. One of the genes associated with X-linked mental retardation is the ZDHHC15 gene.

The ZDHHC15 gene is located on the X chromosome and provides instructions for making a protein called palmitoyltransferase ZDHHC15. This protein is involved in the modification of other proteins by adding a fatty acid called palmitate. Palmitoylation is essential for the proper functioning of many proteins, including those involved in communication between nerve cells.

Symptoms

X-linked mental retardation caused by mutations in the ZDHHC15 gene is also known as mental retardation, X-linked type 91 (MRX91). The symptoms of MRX91 vary in severity, but typically include:

• Intellectual disability
• Delayed speech and language development
• Behavioral problems, such as hyperactivity and aggression
• Seizures
• Abnormal facial features, such as a small head size and a prominent forehead

Diagnosis

Diagnosis of MRX91 is based on clinical evaluation, family history, and genetic testing. Genetic testing can confirm the presence of a mutation in the ZDHHC15 gene, which is the cause of MRX91. Next-generation sequencing (NGS) is a powerful tool for genetic testing, which can simultaneously analyze multiple genes, including the ZDHHC15 gene.

NGS Genetic DNA Test Cost

The cost of NGS genetic DNA testing for MRX91 varies depending on the laboratory and the specific tests performed. At DNA Labs India, the cost of NGS genetic DNA testing for MRX91 is INR 20,000.

Conclusion

X-linked mental retardation caused by mutations in the ZDHHC15 gene is a rare genetic disorder that primarily affects males. The symptoms of MRX91 vary in severity, but typically include intellectual disability, delayed speech and language development, behavioral problems, seizures, and abnormal facial features. Diagnosis of MRX91 is based on clinical evaluation, family history, and genetic testing, including NGS genetic DNA testing. The cost of NGS genetic DNA testing for MRX91 at DNA Labs India is INR 20,000.

If you suspect that you or a loved one may have MRX91, it is important to seek medical advice and genetic counseling. Genetic counseling can help you understand the risks and benefits of genetic testing, as well as the implications of a positive or negative test result.

At DNA Labs India, we are committed to providing accurate and reliable genetic testing services to our clients. Our state-of-the-art laboratory and experienced team of geneticists and scientists ensure that our tests are of the highest quality. For more information about our NGS genetic DNA testing services, please contact us.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for ZDHHC15 Gene Mental retardation, X-linked type 91 NGS Genetic DNA Test