Short Description

NGS genetic DNA test detecets for variant and mutation detection in ZBTB24 gene for Immunodeficiency-centromeric instability-facial anomalies syndrome type 2

PreTest Information

Clinical History of Patient who is going for ZBTB24 Gene Immunodeficiency-centromeric instability-facial anomalies syndrome type 2 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with ZBTB24 Gene Immunodeficiency-centromeric instability-facial anomalies syndrome type 2 NGS Genetic DNA Test gene ZBTB24

Detail Description

ZBTB24 Gene Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome Type 2 NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

ZBTB24 Gene Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome Type 2 (ICF2) is a rare genetic disorder that affects the immune system, causing recurrent infections and other health problems. ICF2 is caused by mutations in the ZBTB24 gene, which plays a crucial role in regulating the production of immune cells.

Symptoms of ICF2

The symptoms of ICF2 can vary widely between individuals, but some of the most common symptoms include:

• Recurrent infections, including respiratory infections, ear infections, and sinus infections
• Chronic diarrhea
• Failure to thrive in infancy
• Growth delays
• Developmental delays
• Facial anomalies, including a small head size, a small jaw, and a flat or broad nasal bridge
• Abnormal tooth development
• Intellectual disability

Diagnosis of ICF2

ICF2 is typically diagnosed through genetic testing, which can identify mutations in the ZBTB24 gene. Next-generation sequencing (NGS) is the most common type of genetic testing used to diagnose ICF2. NGS allows for the simultaneous analysis of multiple genes, making it a highly efficient and cost-effective way to diagnose genetic disorders.

NGS Genetic DNA Test Cost

The cost of an NGS genetic DNA test for ICF2 is typically around INR 20,000. This cost can vary depending on the specific laboratory that performs the test and the country in which the test is performed.

Conclusion

ICF2 is a rare genetic disorder that can cause a range of health problems, including recurrent infections, developmental delays, and facial anomalies. Genetic testing, including NGS, is the most reliable way to diagnose ICF2. If you or a loved one are experiencing symptoms of ICF2, speak to a healthcare provider about genetic testing options.

If you need genetic testing services for ZBTB24 Gene Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome Type 2 in India, DNA Labs India can provide you with the necessary testing services. Contact us today to learn more about our genetic testing services.