Short Description

NGS genetic DNA test detecets for variant and mutation detection in XPC gene for Xeroderma pigmentosum, group C

PreTest Information

Clinical History of Patient who is going for XPC Gene Xeroderma pigmentosum, group C NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with XPC Gene Xeroderma pigmentosum, group C NGS Genetic DNA Test gene XPC

Detail Description

XPC Gene Xeroderma Pigmentosum, Group C NGS Genetic DNA Test

Do you have a family history of skin cancer or notice unusual skin lesions that do not heal? It could be a sign of Xeroderma Pigmentosum (XP), a rare genetic disorder that makes the skin extremely sensitive to ultraviolet (UV) radiation and increases the risk of skin cancer. Xeroderma Pigmentosum is caused by mutations in genes that regulate the body's ability to repair DNA damage caused by UV radiation.

One such gene is the XPC gene, which codes for a protein that recognizes and repairs DNA damage caused by UV radiation. Mutations in the XPC gene can lead to Xeroderma Pigmentosum, Group C (XP-C), a subtype of the disorder that affects approximately 30% of people with XP.

Symptoms of Xeroderma Pigmentosum, Group C

XP-C typically appears in childhood and is characterized by extreme sensitivity to UV radiation, causing skin damage and lesions in sun-exposed areas. The symptoms of XP-C include:

• Freckles and pigmentation changes on the skin
• Dry and rough skin
• Premature aging of the skin
• Skin cancers, including melanoma, basal cell carcinoma, and squamous cell carcinoma

Diagnosis of Xeroderma Pigmentosum, Group C

If you or your family members have symptoms of Xeroderma Pigmentosum, your doctor may recommend a genetic DNA test to check for mutations in the XPC gene. The NGS Genetic DNA Test is a comprehensive genetic test that can detect mutations in multiple genes associated with XP.

The NGS Genetic DNA Test involves taking a small blood sample, which is then analyzed in a laboratory using advanced genetic sequencing techniques. The test can identify mutations in the XPC gene and other genes associated with XP, providing a definitive diagnosis of the disorder.

The Cost of NGS Genetic DNA Test for Xeroderma Pigmentosum, Group C

The cost of NGS Genetic DNA Test for Xeroderma Pigmentosum, Group C in India is approximately INR 20,000. The test is available at DNA Labs India, a leading genetic testing laboratory in the country.

Conclusion

Xeroderma Pigmentosum, Group C is a rare genetic disorder that can cause severe skin damage and increase the risk of skin cancer. If you or your family members have symptoms of XP, it is important to get a genetic DNA test to check for mutations in the XPC gene. The NGS Genetic DNA Test is a comprehensive test that can provide a definitive diagnosis of XP and help you take the necessary steps to manage the disorder.

For more information about the NGS Genetic DNA Test for Xeroderma Pigmentosum, Group C and other genetic tests, contact DNA Labs India.