Short Description

Wilm's tumour tumor suppressor gene1 (WT1) causes an embryonic malignancy of the kidney. It occurs in both sporadic and hereditary forms. Inactivation of WT1 causes Wilm's tumour, and Denys-Drash syndrome (DDS), leading to nephropathy and genital abnormalities.

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

WT-1 MUTATION DETECTION Test Cost INR: 12000

WT-1 mutation detection test is a genetic test that is used to identify mutations in the WT1 gene. This gene is responsible for regulating the growth and development of certain cells in the body, including kidney cells. Mutations in this gene can lead to the development of Wilms tumor, a type of kidney cancer that is most commonly diagnosed in children.

Symptoms of Wilms Tumor

The symptoms of Wilms tumor can vary depending on the stage of the cancer. In its early stages, Wilms tumor may not cause any symptoms. However, as the cancer grows, it can cause the following symptoms:

• Abdominal pain or swelling
• Blood in the urine
• Fever
• Loss of appetite
• Nausea or vomiting
• Fatigue or weakness

Diagnosis of Wilms Tumor

Wilms tumor is typically diagnosed using a combination of imaging tests, such as ultrasound, CT scans, and MRI scans, as well as a biopsy of the tumor. Genetic testing can also be used to identify mutations in the WT1 gene, which can help with diagnosis and treatment planning.

WT-1 Mutation Detection Test

The WT-1 mutation detection test is a genetic test that is used to identify mutations in the WT1 gene. This test can help with the diagnosis of Wilms tumor and can also be used to identify individuals who are at an increased risk of developing the cancer.

The cost of the WT-1 mutation detection test in India is INR 12000. The test can be performed at DNA Labs India, a leading provider of genetic testing services in the country.

Conclusion

The WT-1 mutation detection test is an important tool for the diagnosis and treatment of Wilms tumor. It can help identify individuals who are at an increased risk of developing the cancer and can also help with treatment planning. If you or a loved one is experiencing symptoms of Wilms tumor, it is important to speak with a healthcare provider and consider genetic testing.

Contact DNA Labs India to learn more about the WT-1 mutation detection test and other genetic testing services.

Wilm's tumour tumor suppressor gene1 (WT1) causes an embryonic malignancy of the kidney. It occurs in both sporadic and hereditary forms. Inactivation of WT1 causes Wilm's tumour, and Denys-Drash syndrome (DDS), leading to nephropathy and genital abnormalities.