Short Description

Very Long Chain Fatty Acids (VLCFAs), Phytanic acid and Pristanic acid are metabolized by Peroxisomes. Defects in these pathways usually result in the accumulation in tissues and body fluids of one or more metabolites derived from the blocked metabolic steps. This assay is used for differential diagnosis of peroxisomal disorders like Zellweger spectrum disorders of peroxisomal biogenesis, X-linked Adrenoleukodystrophy (X-ALD) and its adult form X-linked Adrenomyeloneuropathy (X-AMN), Refsum disease (Phytanoyl-CoA hydroxylase Deficiency) & 2-methylacyl-CoA racemase deficiency.

PreTest Information

Avoid alcohol 24 hours prior to sample collection. Overnight fasting is mandatory. For pediatric patients, fasting is not required but sample collection should occur prior to the next meal or scheduled feeding. Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Detail Description

Understanding Very Long Chain Fatty Acids Test

Very long chain fatty acids are a type of fatty acid that plays a crucial role in the proper functioning of our body. These fatty acids are found in the membranes of our cells and are essential for the production of hormones and the maintenance of healthy skin and hair. However, when there is an abnormality in the metabolism of very long chain fatty acids, it can lead to a range of health problems.

The Very Long Chain Fatty Acids Test is a diagnostic test that measures the levels of very long chain fatty acids in the blood. It is used to diagnose a group of metabolic disorders known as peroxisomal disorders. These disorders are characterized by the inability of the peroxisomes, which are tiny structures in our cells, to break down very long chain fatty acids properly.

Why is the Very Long Chain Fatty Acids Test important?

The Very Long Chain Fatty Acids Test is an important test as it helps in the diagnosis of peroxisomal disorders. These disorders can have serious consequences if left untreated, including developmental delays, seizures, vision and hearing problems, liver disease, and even death. Early diagnosis of peroxisomal disorders is crucial to prevent these complications and provide appropriate treatment.

What are the symptoms of peroxisomal disorders?

The symptoms of peroxisomal disorders can vary widely depending on the specific disorder. Some common symptoms include:

• Developmental delays
• Seizures
• Vision and hearing problems
• Liver disease
• Abnormal bone development
• Abnormal facial features

If you or your child are experiencing any of these symptoms, it is important to consult a doctor for further evaluation.

How is the Very Long Chain Fatty Acids Test performed?

The Very Long Chain Fatty Acids Test is a simple blood test that can be performed at any laboratory. The test involves drawing a small sample of blood from a vein in the arm. The blood sample is then sent to a laboratory for analysis.

What is the cost of the Very Long Chain Fatty Acids Test?

The cost of the Very Long Chain Fatty Acids Test in India is approximately INR 35,000. However, the cost may vary depending on the laboratory and location.

Conclusion

The Very Long Chain Fatty Acids Test is an important diagnostic test that can help in the early diagnosis of peroxisomal disorders. If you or your child are experiencing any symptoms of these disorders, it is important to consult a doctor for further evaluation. The cost of the test may vary depending on the laboratory and location, but it is a small price to pay for early detection and appropriate treatment.

If you are looking for a reliable laboratory to perform the Very Long Chain Fatty Acids Test, DNA Labs India is a leading diagnostic laboratory in India that offers a wide range of tests at affordable prices. Contact us today to schedule an appointment.

Very Long Chain Fatty Acids (VLCFAs), Phytanic acid and Pristanic acid are metabolized by Peroxisomes. Defects in these pathways usually result in the accumulation in tissues and body fluids of one or more metabolites derived from the blocked metabolic steps. This assay is used for differential diagnosis of peroxisomal disorders like Zellweger spectrum disorders of peroxisomal biogenesis, X-linked Adrenoleukodystrophy (X-ALD) and its adult form X-linked Adrenomyeloneuropathy (X-AMN), Refsum disease (Phytanoyl-CoA hydroxylase Deficiency) & 2-methylacyl-CoA racemase deficiency.