Short Description

NGS genetic DNA test detecets for variant and mutation detection in TTR gene for Amyloidosis

PreTest Information

Clinical History of Patient who is going for TTR Gene Amyloidosis NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with TTR Gene Amyloidosis

Detail Description

TTR Gene Amyloidosis NGS Genetic DNA Test: Symptoms, Diagnosis, and Cost in India

Are you experiencing symptoms such as numbness, tingling, or weakness in your limbs? Or are you having heart problems such as irregular heartbeats or shortness of breath? These symptoms could be caused by a genetic disorder known as TTR gene amyloidosis.

TTR gene amyloidosis is a rare genetic disorder that affects the nervous system and the heart. It is caused by mutations in the TTR gene, which produces a protein called transthyretin. The mutated protein can form amyloid deposits in various organs and tissues in the body, causing damage and dysfunction.

Symptoms

The symptoms of TTR gene amyloidosis can vary depending on the type and severity of the disease. There are three main types of TTR gene amyloidosis:

• Hereditary ATTR amyloidosis
• Wild-type ATTR amyloidosis
• Senile systemic amyloidosis

The most common symptoms of TTR gene amyloidosis include:

• Numbness, tingling, or weakness in the limbs
• Heart problems such as irregular heartbeats, shortness of breath, and swelling in the legs
• Gastrointestinal problems such as constipation, diarrhea, and weight loss
• Eye problems such as dry eyes and blurred vision

Diagnosis

TTR gene amyloidosis can be difficult to diagnose because its symptoms can be similar to those of other diseases. However, there are several tests that can help diagnose the condition:

• Blood tests to measure the levels of transthyretin and other proteins
• Genetic testing to identify mutations in the TTR gene
• Nerve conduction studies to evaluate the function of the nerves
• Heart tests such as echocardiography and electrocardiography
• Gastrointestinal tests such as endoscopy and biopsy

TTR Gene Amyloidosis NGS Genetic DNA Test

NGS (next-generation sequencing) is a powerful technology that can analyze multiple genes at once, providing a comprehensive genetic analysis. TTR gene amyloidosis NGS genetic DNA test is a diagnostic test that uses NGS technology to analyze the TTR gene for mutations. The test can identify mutations that cause TTR gene amyloidosis and provide information about the severity of the disease.

The cost of TTR gene amyloidosis NGS genetic DNA test in India is around INR 20,000. The test is usually covered by insurance, but it is advisable to check with your insurance provider beforehand.

Conclusion

TTR gene amyloidosis is a rare genetic disorder that can cause a range of symptoms such as numbness, tingling, and heart problems. If you are experiencing any of these symptoms, it is important to consult a doctor and undergo diagnostic tests such as the TTR gene amyloidosis NGS genetic DNA test. Early diagnosis and treatment can help manage the symptoms and improve the quality of life.

At DNA Labs India, we provide TTR gene amyloidosis NGS genetic DNA test and other genetic tests that can help diagnose and manage genetic disorders. Contact us to learn more about our services.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TTR Gene Amyloidosis NGS Genetic DNA Test