Short Description

NGS genetic DNA test detecets for variant and mutation detection in TRPM7 gene for Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to

PreTest Information

Clinical History of Patient who is going for TRPM7 Gene Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with TRPM7 Gene Amyotrophic lateral sclerosis-parkinsonism/dementia complex, susceptibility to

Detail Description

TRPM7 Gene and Its Susceptibility to Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects the nerve cells in the brain and spinal cord, leading to muscle weakness, paralysis, and eventually death. Parkinsonism and dementia complex are also common neurological disorders that affect the motor and cognitive functions of the brain. The TRPM7 gene has been identified as a potential risk factor for the development of ALS-parkinsonism/dementia complex.

Symptoms and Diagnosis

The symptoms of ALS-parkinsonism/dementia complex can vary depending on the individual and the stage of the disease. Some common symptoms include:

• Muscle weakness and stiffness
• Tremors or shaking
• Difficulty speaking or swallowing
• Memory loss and cognitive impairment
• Depression and anxiety

Diagnosis of ALS-parkinsonism/dementia complex can be challenging, as there is no single test that can definitively diagnose the disease. Doctors typically perform a thorough physical examination and a series of neurological tests to evaluate the patient's symptoms. Imaging tests such as MRI or CT scans may also be used to rule out other conditions that may mimic ALS-parkinsonism/dementia complex.

NGS Genetic DNA Test

Advancements in genetic testing have made it possible to identify genetic risk factors for ALS-parkinsonism/dementia complex. The next-generation sequencing (NGS) genetic DNA test can analyze multiple genes simultaneously, providing a more comprehensive view of a patient's genetic makeup. The TRPM7 gene is one of the genes that can be analyzed using NGS testing.

Cost of NGS Genetic DNA Test

The cost of NGS genetic DNA testing for TRPM7 gene susceptibility to ALS-parkinsonism/dementia complex in India is approximately INR 20,000. The exact cost may vary depending on the testing facility and the specific tests performed.

Conclusion

ALS-parkinsonism/dementia complex is a complex neurological disorder that can have a significant impact on a patient's quality of life. Genetic testing, such as NGS testing for TRPM7 gene susceptibility, can help identify potential risk factors and aid in early diagnosis and treatment. If you or a loved one is experiencing symptoms of ALS-parkinsonism/dementia complex, it is important to seek medical attention and consider genetic testing as part of your diagnostic evaluation.

At DNA Labs India, we offer comprehensive genetic testing services for a variety of neurological disorders. Contact us today to learn more about our testing options and how we can help you.