Short Description

NGS genetic DNA test detecets for variant and mutation detection in TNFAIP3 gene for Rheumatoid arthritis, TNFAIP3 related

PreTest Information

Clinical History of Patient who is going for TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic DNA Test gene TNFAIP3

Detail Description

TNFAIP3 Gene and Rheumatoid Arthritis: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Rheumatoid arthritis is a chronic autoimmune disorder that primarily affects the joints. It is characterized by inflammation, pain, stiffness, and swelling in the affected joints. While the exact cause of rheumatoid arthritis is not known, genetic factors are believed to play a significant role in its development. One such gene that has been linked to rheumatoid arthritis is TNFAIP3.

TNFAIP3 Gene and Rheumatoid Arthritis

The TNFAIP3 gene, also known as A20, is responsible for producing a protein that regulates the immune system. This protein helps to prevent excessive inflammation and damage to the body's own tissues. In people with rheumatoid arthritis, there is a mutation in the TNFAIP3 gene that leads to reduced production of the A20 protein. This, in turn, results in increased inflammation and damage to the joints.

Symptoms of Rheumatoid Arthritis

The symptoms of rheumatoid arthritis can vary from person to person. However, some common symptoms include:

• Pain and stiffness in the joints, especially in the morning or after periods of inactivity
• Swelling and tenderness in the joints
• Reduced range of motion in the affected joints
• Fatigue and general weakness
• Fever and weight loss (in severe cases)

Diagnosis of Rheumatoid Arthritis

Diagnosing rheumatoid arthritis can be challenging, as its symptoms are similar to those of other conditions. However, some tests can help to confirm the diagnosis, including:

• Blood tests to detect the presence of rheumatoid factor and anti-cyclic citrullinated peptide (anti-CCP) antibodies
• Imaging tests such as X-rays, MRI, and ultrasound to assess joint damage and inflammation
• Physical examination to assess joint tenderness, swelling, and range of motion

NGS Genetic DNA Test Cost

NGS Genetic DNA Test is a diagnostic test that uses Next Generation Sequencing (NGS) technology to analyze a patient's DNA. This test can help to identify mutations in the TNFAIP3 gene that may be associated with rheumatoid arthritis. The cost of NGS Genetic DNA Test for TNFAIP3-related rheumatoid arthritis in India is approximately INR 20,000.

Conclusion

Rheumatoid arthritis is a debilitating condition that can significantly impact a person's quality of life. Understanding the role of genes such as TNFAIP3 in its development can help to improve diagnosis and treatment. If you are experiencing symptoms of rheumatoid arthritis, it is essential to consult a healthcare professional for proper diagnosis and management.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TNFAIP3 Gene Rheumatoid arthritis, TNFAIP3 related NGS Genetic DNA Test