Short Description

NGS genetic DNA test detecets for variant and mutation detection in TGM6 gene for Spinocerebellar ataxia type 35, autosomal dominant

PreTest Information

Clinical History of Patient who is going for TGM6 Gene Spinocerebellar ataxia type 35, autosomal dominant NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with TGM6 Gene Spinocerebellar ataxia type 35, autosomal dominant

Detail Description

TGM6 Gene Spinocerebellar Ataxia Type 35: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Spinocerebellar ataxia type 35 (SCA35) is a rare genetic disorder that affects the nervous system. It is caused by a mutation in the TGM6 gene, which provides instructions for making an enzyme called transglutaminase 6. This enzyme is involved in the normal functioning of the cerebellum, which is the part of the brain that controls movement and coordination.

Symptoms of SCA35

SCA35 usually begins in mid-adulthood and progresses slowly over many years. The symptoms can vary widely from person to person, but may include:

• Loss of coordination and balance
• Trouble walking and standing
• Slurred speech
• Tremors or shaking
• Difficulty with fine motor skills, such as writing or buttoning clothes
• Memory problems

Diagnosis of SCA35

SCA35 can be difficult to diagnose because it is rare and the symptoms can be similar to other conditions. However, genetic testing can confirm the presence of the TGM6 mutation that causes the disorder.

NGS (Next-Generation Sequencing) Genetic DNA testing is a powerful tool for identifying genetic mutations. It allows for the simultaneous analysis of multiple genes, including the TGM6 gene. This test can be performed on a blood sample and provides a comprehensive analysis of an individual's genetic makeup.

NGS Genetic DNA Test Cost in India

The cost of an NGS Genetic DNA test for SCA35 in India can vary depending on the laboratory and the specific test being performed. However, on average, the cost of this test is around INR 20,000. It is important to note that insurance coverage for genetic testing can vary and individuals should check with their insurance provider to determine coverage.

Conclusion

SCA35 is a rare genetic disorder that can be difficult to diagnose. However, with the use of NGS Genetic DNA testing, individuals can receive a comprehensive analysis of their genetic makeup and confirm the presence of the TGM6 mutation that causes the disorder. The cost of this test in India is around INR 20,000, but insurance coverage may vary. Early diagnosis and treatment can help individuals manage their symptoms and improve their quality of life.

Contact DNA Labs India for more information on NGS Genetic DNA testing for SCA35 and other genetic disorders.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TGM6 Gene Spinocerebellar ataxia type 35, autosomal dominant NGS Genetic DNA Test