Short Description

NGS genetic DNA test detecets for variant and mutation detection in TAC3 gene for Hypogonadotropic hypogonadism type 10 with or without anosmia

PreTest Information

Clinical History of Patient who is going for TAC3 Gene Hypogonadotropic hypogonadism type 10 with or without anosmia NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TAC3 Gene Hypogonadotropic hypogonadism type 10 with or without anosmia NGS Genetic DNA Test gene TAC3

Detail Description

TAC3 Gene Hypogonadotropic hypogonadism type 10 with or without anosmia NGS Genetic DNA Test cost INR:20000 symptoms diagnosis

Hypogonadotropic hypogonadism (HH) is a condition that affects the reproductive system of both males and females. It is caused by the insufficient production of gonadotropin-releasing hormone (GnRH), which regulates the production of sex hormones. HH can be classified into two types: congenital (CHH) and acquired (AHH). CHH is caused by genetic mutations, while AHH is usually caused by stress, medications, or other medical conditions.

TAC3 gene hypogonadotropic hypogonadism type 10 with or without anosmia is a rare form of CHH that is caused by mutations in the TAC3 gene. The TAC3 gene provides instructions for making a protein called neurokinin B, which is involved in the regulation of GnRH production. Individuals with this condition may experience delayed or absent puberty, infertility, and other symptoms related to low levels of sex hormones.

Symptoms

The symptoms of TAC3 gene hypogonadotropic hypogonadism type 10 with or without anosmia can vary from person to person. Some of the common symptoms include:

• Delayed or absent puberty
• Infertility
• Decreased libido
• Decreased muscle mass
• Decreased bone density
• Hot flashes
• Fatigue

Individuals with this condition may also have anosmia, which is the loss of the sense of smell. This is because the TAC3 gene is also involved in the development of the olfactory system.

Diagnosis

TAC3 gene hypogonadotropic hypogonadism type 10 with or without anosmia can be diagnosed through genetic testing. Next-generation sequencing (NGS) is a powerful tool that can analyze multiple genes at once, making it an efficient way to screen for genetic disorders. A blood sample is taken from the patient, and the DNA is extracted and sequenced. The results are then analyzed to determine if there are any mutations in the TAC3 gene.

Cost

The cost of the TAC3 gene hypogonadotropic hypogonadism type 10 with or without anosmia NGS genetic DNA test in India is around INR 20,000. This cost may vary depending on the testing facility and any additional tests that may be required.

Conclusion

TAC3 gene hypogonadotropic hypogonadism type 10 with or without anosmia is a rare genetic disorder that can cause a range of symptoms related to low levels of sex hormones. Genetic testing using NGS technology can be an effective way to diagnose this condition. If you or someone you know is experiencing symptoms related to hypogonadism, it is important to speak with a healthcare provider to determine the underlying cause and appropriate treatment.

At DNA Labs India, we offer a range of genetic tests, including the TAC3 gene hypogonadotropic hypogonadism type 10 with or without anosmia NGS genetic DNA test, to help individuals and families better understand their genetic risks and make informed decisions about their health. Contact us today to learn more.