Short Description

NGS genetic DNA test detecets for variant and mutation detection in TAB2 gene for Congenital heart defects multiple types

PreTest Information

Clinical History of Patient who is going for TAB2 Gene Congenital heart defects multiple types NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TAB2 Gene Congenital heart defects multiple types NGS Genetic DNA Test gene TAB2

Detail Description

TAB2 Gene Congenital Heart Defects: Multiple Types NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

Congenital heart defects (CHDs) are structural problems in the heart that are present at birth. According to the Centers for Disease Control and Prevention (CDC), CHDs affect nearly 1% of births in the United States. While some CHDs are mild and may not require treatment, others can be life-threatening and require immediate medical attention.

One gene that has been linked to CHDs is the TAB2 gene. In this blog, we will discuss the TAB2 gene, its role in CHDs, the symptoms of CHDs, and the diagnosis and cost of NGS genetic DNA testing.

The TAB2 Gene and Congenital Heart Defects

The TAB2 gene is located on chromosome 6 and codes for a protein that is involved in signaling pathways that regulate inflammation and cell survival. Studies have shown that mutations in the TAB2 gene can lead to various types of CHDs, including:

• Ventricular septal defects (VSDs)
• Atrial septal defects (ASDs)
• Tetralogy of Fallot
• Transposition of the great arteries (TGA)

VSDs and ASDs are the most common types of CHDs and involve holes in the walls that separate the heart chambers. Tetralogy of Fallot is a more complex CHD that involves four defects in the heart, while TGA involves the reversal of the pulmonary artery and aorta.

Symptoms of Congenital Heart Defects

The symptoms of CHDs can vary depending on the type and severity of the defect. Some babies may not show any symptoms, while others may experience:

• Rapid breathing or difficulty breathing
• Cyanosis (blue tint to the skin, lips, and nails)
• Swelling in the legs, abdomen, or around the eyes
• Poor feeding or difficulty gaining weight
• Fatigue or weakness

In some cases, CHDs may not be diagnosed until later in life when symptoms appear, or during routine medical exams.

Diagnosis and NGS Genetic DNA Test Cost

The diagnosis of CHDs typically involves a physical exam, medical history, and diagnostic tests such as:

• Echocardiogram
• Chest X-ray
• Electrocardiogram (ECG)
• Cardiac catheterization

NGS genetic DNA testing can also be used to diagnose CHDs and identify any genetic mutations that may be present. The cost of NGS genetic DNA testing for the TAB2 gene and other CHD-related genes in India can range from INR 20,000 to INR 50,000, depending on the specific test and the laboratory performing the test.

Conclusion

While CHDs can be a serious and sometimes life-threatening condition, early diagnosis and treatment can greatly improve outcomes. The TAB2 gene has been linked to various types of CHDs, and NGS genetic DNA testing can be a useful tool in identifying any genetic mutations that may be present. If you suspect that you or your child may have a congenital heart defect, it is important to speak with a medical professional for proper diagnosis and treatment.

At DNA Labs India, we offer a range of genetic testing services, including NGS genetic DNA testing for congenital heart defects. Contact us today to learn more about our services and how we can help.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TAB2 Gene Congenital heart defects multiple types NGS Genetic DNA Test