Short Description

NGS genetic DNA test detecets for variant and mutation detection in SYNJ1 gene for PARK20 Parkinson

PreTest Information

Clinical History of Patient who is going for SYNJ1 Gene PARK20 Parkinson NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with SYNJ1 Gene PARK20 Parkinson

Detail Description

SYNJ1 Gene PARK20 Parkinson NGS Genetic DNA Test

DNA Labs India provides advanced genetic testing services for a range of genetic disorders. One such disorder is Parkinson's disease, which is caused by a range of genetic mutations. The SYNJ1 gene is one such gene that has been linked to Parkinson's disease. Our PARK20 Parkinson NGS Genetic DNA Test helps diagnose Parkinson's disease caused by mutations in the SYNJ1 gene.

What is Parkinson's disease?

Parkinson's disease is a neurodegenerative disorder that affects the central nervous system. It is characterized by the progressive loss of dopamine-producing neurons in the brain, leading to the development of symptoms such as tremors, rigidity, and difficulty in movement. Parkinson's disease affects around 1% of the population over the age of 60 and is more common in men than women.

What is the SYNJ1 gene?

The SYNJ1 gene is located on chromosome 21 and codes for a protein called synaptojanin-1. This protein is involved in the formation and recycling of synaptic vesicles, which are essential for the communication between neurons in the brain. Mutations in the SYNJ1 gene have been linked to the development of Parkinson's disease, particularly in individuals with a family history of the disease.

PARK20 Parkinson NGS Genetic DNA Test

The PARK20 Parkinson NGS Genetic DNA Test offered by DNA Labs India helps diagnose Parkinson's disease caused by mutations in the SYNJ1 gene. This test uses next-generation sequencing (NGS) technology to analyze the entire coding region of the SYNJ1 gene and identify any mutations that may be present. The test is performed using a blood sample and has a turnaround time of around 4-6 weeks.

Symptoms of Parkinson's disease

The symptoms of Parkinson's disease can vary from person to person and can range from mild to severe. Some common symptoms include:

• Tremors or shaking of the hands, arms, legs, or jaw
• Stiffness or rigidity of the limbs and trunk
• Slowness of movement or bradykinesia
• Difficulty in initiating movements or freezing of gait
• Loss of balance or coordination

Diagnosis of Parkinson's disease

Diagnosis of Parkinson's disease is based on a combination of clinical symptoms and medical history. However, genetic testing can be useful in certain cases, particularly when there is a family history of the disease or when the onset of symptoms is at an early age. The PARK20 Parkinson NGS Genetic DNA Test offered by DNA Labs India can help diagnose Parkinson's disease caused by mutations in the SYNJ1 gene.

Cost of PARK20 Parkinson NGS Genetic DNA Test

The cost of the PARK20 Parkinson NGS Genetic DNA Test offered by DNA Labs India is INR 20,000. This includes the cost of the test, genetic counseling, and interpretation of the results.

Conclusion

The PARK20 Parkinson NGS Genetic DNA Test offered by DNA Labs India is a useful tool in the diagnosis of Parkinson's disease caused by mutations in the SYNJ1 gene. This test can help individuals with a family history of the disease or those with early onset symptoms get an accurate diagnosis and appropriate treatment. The test is affordable and can be performed using a simple blood sample.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SYNJ1 Gene PARK20 Parkinson NGS Genetic DNA Test