Short Description

Succinylacetone is the primary marker for detection of Tyrosinemia Type 1 where Tyrosine concentration may or may not be elevated. Normal levels may be seen in affected individuals undergoing treatment.

PreTest Information

Give brief clinical history.

Detail Description

SUCCINYLACETONE URINE Test cost INR:5000 symptoms diagnosis

If you or a loved one is experiencing symptoms like vomiting, jaundice, and liver enlargement, it's important to get a proper diagnosis and treatment plan. One test that may be recommended is the succinylacetone urine test. In this blog, we'll discuss the cost of the test, as well as its symptoms and diagnosis.

What is the succinylacetone urine test?

The succinylacetone urine test is a medical test used to detect the presence of succinylacetone in urine. Succinylacetone is a chemical that is produced in the body when there is a deficiency in the enzyme called porphobilinogen deaminase (PBGD). This enzyme is responsible for the production of heme, a component of hemoglobin, which is important for the oxygen-carrying capacity of red blood cells.

A deficiency in PBGD can lead to a rare genetic disorder called hereditary tyrosinemia type 1 (HT1), which can cause liver damage and failure if left untreated. The succinylacetone urine test is used to screen for HT1 in newborn babies and to monitor the condition in individuals who have already been diagnosed with the disorder.

Symptoms of HT1

HT1 is a rare disorder, but it can have serious consequences if left untreated. The symptoms of HT1 may include:

• Vomiting
• Jaundice (yellowing of the skin and eyes)
• Abdominal pain and swelling
• Poor weight gain and growth
• Enlarged liver and spleen
• Developmental delays

If you or your child is experiencing any of these symptoms, it's important to seek medical attention right away.

Diagnosing HT1

If a doctor suspects that a patient has HT1, they may order a variety of tests to confirm the diagnosis. One of these tests is the succinylacetone urine test. This test involves collecting a urine sample from the patient and sending it to a lab for analysis.

The cost of the succinylacetone urine test may vary depending on the lab where it's performed. At DNA Labs India, the cost of the test is INR 5000.

If the succinylacetone urine test comes back positive for HT1, further testing may be needed to confirm the diagnosis. This may include a blood test to measure levels of amino acids and other chemicals in the blood, as well as a liver biopsy to evaluate the extent of liver damage.

Treating HT1

If a patient is diagnosed with HT1, treatment typically involves a combination of medications and dietary changes. Medications may be used to help reduce the levels of toxic substances in the body, while dietary changes may involve avoiding certain foods that can exacerbate the condition.

In severe cases of HT1, a liver transplant may be necessary to prevent liver failure and other complications.

Conclusion

The succinylacetone urine test is an important tool for diagnosing hereditary tyrosinemia type 1. If you or a loved one is experiencing symptoms of the disorder, it's important to seek medical attention right away and discuss the possibility of undergoing the succinylacetone urine test. While the cost of the test may vary, it's an investment in your health and wellbeing.

For more information on the succinylacetone urine test or other medical tests, contact DNA Labs India today.

Succinylacetone is the primary marker for detection of Tyrosinemia Type 1 where Tyrosine concentration may or may not be elevated. Normal levels may be seen in affected individuals undergoing treatment.