Short Description

NGS genetic DNA test detecets for variant and mutation detection in SPG21 gene for SPG21

PreTest Information

Clinical History of Patient who is going for SPG21 Gene SPG21 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with SPG21 Gene SPG21

Detail Description

SPG21 Gene: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

SPG21 gene mutation is a rare genetic disorder that affects the nervous system and causes a group of neurological disorders called hereditary spastic paraplegias (HSP). HSP is characterized by progressive stiffness and weakness in the legs, leading to difficulty in walking and mobility.

Symptoms of SPG21 Gene Mutation

The symptoms of SPG21 gene mutation can vary depending on the severity and type of mutation. However, some common symptoms include:

• Difficulty in walking and mobility
• Stiffness and weakness in the legs
• Abnormal gait
• Foot dragging
• Muscle spasms
• Urinary urgency
• Difficulty in coordination and balance
• Speech difficulties

These symptoms usually start in early childhood or adolescence and progress slowly over time. In some cases, the symptoms may worsen rapidly, leading to severe disability.

Diagnosis of SPG21 Gene Mutation

Diagnosis of SPG21 gene mutation involves a thorough physical examination and genetic testing. A neurologist or geneticist may perform the following tests:

• Physical examination to check for muscle weakness, stiffness, and reflexes
• Imaging tests such as MRI or CT scan to check for abnormalities in the brain and spinal cord
• Genetic testing to identify mutations in the SPG21 gene

If a patient is diagnosed with SPG21 gene mutation, their family members may also need to undergo genetic testing to determine if they have inherited the mutation.

NGS Genetic DNA Test Cost for SPG21 Gene Mutation in India

NGS Genetic DNA Test for SPG21 gene mutation is a specialized genetic test that uses next-generation sequencing technology to identify mutations in the SPG21 gene. The cost of the test in India can vary depending on the laboratory and location, but it usually ranges from INR 20,000 to INR 30,000.

DNA Labs India is a leading genetic testing laboratory in India that offers NGS Genetic DNA Test for SPG21 gene mutation. The laboratory uses state-of-the-art equipment and technology to provide accurate and reliable results. The cost of the test at DNA Labs India is INR 20,000.

Conclusion

SPG21 gene mutation is a rare genetic disorder that affects the nervous system and causes hereditary spastic paraplegias. Early diagnosis and genetic testing can help in the management and treatment of the disorder. NGS Genetic DNA Test for SPG21 gene mutation is a specialized test that can provide accurate and reliable results. DNA Labs India offers the test at an affordable cost of INR 20,000, making it accessible to patients across India.

If you suspect that you or a family member may have SPG21 gene mutation, it is important to consult a neurologist or geneticist for diagnosis and treatment.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SPG21 Gene SPG21 NGS Genetic DNA Test