Short Description

NGS genetic DNA test detecets for variant and mutation detection in SOX3 gene for Panhypopituitarism, X-linked

PreTest Information

Clinical History of Patient who is going for SOX3 Gene Panhypopituitarism, X-linked NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SOX3 Gene Panhypopituitarism, X-linked NGS Genetic DNA Test gene SOX3

Detail Description

Understanding SOX3 Gene Panhypopituitarism: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost in India

Panhypopituitarism is a medical condition characterized by the underproduction or complete absence of hormones secreted by the pituitary gland. This gland is responsible for controlling various bodily functions, including growth, metabolism, sexual development, and stress response.

One of the genetic causes of panhypopituitarism is the mutation in the SOX3 gene, which is located on the X chromosome. This gene encodes a transcription factor that regulates the development and function of the pituitary gland and the hypothalamus, which controls the pituitary gland.

Symptoms of SOX3 Gene Panhypopituitarism

The symptoms of SOX3 gene panhypopituitarism may vary depending on the severity and age of onset of the condition. Some of the common symptoms include:

• Delayed growth and development
• Short stature
• Delayed puberty or absent secondary sexual characteristics
• Fatigue and weakness
• Weight gain or difficulty losing weight
• Infertility or decreased libido
• Low blood pressure
• Increased sensitivity to cold
• Depression or mood swings

Diagnosis of SOX3 Gene Panhypopituitarism

The diagnosis of SOX3 gene panhypopituitarism is based on a combination of clinical symptoms, hormone level measurements, and genetic testing. Your doctor may perform the following tests:

• Blood tests to measure the levels of pituitary hormones, such as growth hormone, thyroid-stimulating hormone, luteinizing hormone, and follicle-stimulating hormone
• Magnetic resonance imaging (MRI) of the brain to evaluate the structure and function of the pituitary gland and the hypothalamus
• Genetic testing to identify mutations in the SOX3 gene

NGS Genetic DNA Test Cost in India

Next-generation sequencing (NGS) is a high-throughput DNA sequencing technology that can analyze multiple genes simultaneously. NGS genetic testing can identify mutations in the SOX3 gene that cause panhypopituitarism.

The cost of NGS genetic DNA testing in India may vary depending on the laboratory and the specific test. On average, the cost of SOX3 gene NGS testing ranges from INR 20,000 to INR 30,000.

Conclusion

SOX3 gene panhypopituitarism is a rare genetic condition that can cause various hormonal imbalances and growth abnormalities. Early diagnosis and treatment can improve the quality of life and prevent complications. NGS genetic testing can provide accurate and timely diagnosis, and the cost of testing is becoming more affordable with advances in technology.

At DNA Labs India, we offer a wide range of genetic testing services, including NGS testing for SOX3 gene panhypopituitarism. Our experienced team of genetic counselors and scientists can provide personalized guidance and support throughout the testing process. Contact us today to learn more about our services and how we can help you.