Short Description

NGS genetic DNA test detecets for variant and mutation detection in SOD2 gene for Microvascular complications of diabetes type 6, susceptibility to

PreTest Information

Clinical History of Patient who is going for SOD2 Gene Microvascular complications of diabetes type 6, susceptibility to NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Microvascular complications of diabetes type 6, susceptibility to

Detail Description

SOD2 Gene Microvascular Complications of Diabetes Type 6: Susceptibility to NGS Genetic DNA Test

Diabetes is a chronic disease that affects millions of people worldwide. It is characterized by high blood sugar levels that result from the body's inability to produce or properly use insulin. Diabetes can lead to many complications, including microvascular complications that affect small blood vessels in the body. One gene that has been linked to microvascular complications of diabetes is the SOD2 gene.

The SOD2 Gene and Microvascular Complications of Diabetes

The SOD2 gene is responsible for producing an enzyme called superoxide dismutase 2 (SOD2). This enzyme helps to protect cells from damage caused by reactive oxygen species (ROS), which are generated during normal metabolic processes. ROS can cause oxidative stress, which can damage cells and contribute to the development of many diseases, including diabetes.

Studies have shown that mutations in the SOD2 gene can increase the risk of microvascular complications of diabetes. These complications include diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. Diabetic retinopathy affects the blood vessels in the retina and can lead to vision loss. Diabetic neuropathy affects the nerves and can cause pain, numbness, and tingling in the hands and feet. Diabetic nephropathy affects the kidneys and can lead to kidney failure.

NGS Genetic DNA Test for Susceptibility to SOD2 Gene Mutations

NGS (next-generation sequencing) is a powerful tool that can be used to sequence the entire SOD2 gene and identify mutations that may increase the risk of microvascular complications of diabetes. This test can be performed on a small sample of blood or saliva and can provide valuable information about an individual's genetic risk for developing these complications.

The cost of an NGS genetic DNA test for SOD2 gene mutations is INR 20,000. This may seem like a high cost, but it is important to remember that the information gained from this test can be invaluable in preventing or managing microvascular complications of diabetes.

Symptoms and Diagnosis of Microvascular Complications of Diabetes

It is important to recognize the symptoms of microvascular complications of diabetes so that they can be diagnosed and treated early. Symptoms of diabetic retinopathy include blurred vision, floaters, and vision loss. Symptoms of diabetic neuropathy include pain, numbness, and tingling in the hands and feet. Symptoms of diabetic nephropathy include swelling in the legs and feet, fatigue, and nausea.

Diagnosis of microvascular complications of diabetes typically involves a physical exam, blood tests, and imaging tests. A comprehensive eye exam can detect diabetic retinopathy, while nerve conduction studies can detect diabetic neuropathy. A urine test can detect protein in the urine, which is a sign of diabetic nephropathy.

Conclusion

The SOD2 gene plays an important role in protecting cells from oxidative stress, which can contribute to the development of microvascular complications of diabetes. An NGS genetic DNA test can identify mutations in this gene that may increase the risk of these complications. While the cost of this test may seem high, the information gained from it can be invaluable in preventing or managing microvascular complications of diabetes. It is important to recognize the symptoms of these complications and seek prompt medical attention if they occur.

At DNA Labs India, we offer NGS Genetic DNA Testing for SOD2 Gene Microvascular Complications of Diabetes Type 6. Contact us today to learn more about our services and schedule a test.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SOD2 Gene Microvascular complications of diabetes type 6, susceptibility to NGS Genetic DNA Test