Short Description

NGS genetic DNA test detecets for variant and mutation detection in SMARCE1 gene for Meningioma, familial, susceptibility to

PreTest Information

Clinical History of Patient who is going for SMARCE1 Gene Meningioma, familial, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SMARCE1 Gene Meningioma, familial, susceptibility to NGS Genetic DNA Test gene SMARCE1

Detail Description

SMARCE1 Gene Meningioma: Familial Susceptibility and NGS Genetic DNA Test Cost

Meningiomas are tumors that develop from the meninges, which are the thin layers of tissue that cover the brain and spinal cord. These tumors are usually benign, but in some cases, they can become cancerous. SMARCE1 gene meningioma is a type of meningioma that is caused by a genetic mutation in the SMARCE1 gene.

What is the SMARCE1 Gene?

The SMARCE1 gene is located on chromosome 17 and codes for a protein called SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1. This protein is involved in regulating gene expression by altering the structure of chromatin, which is the material that makes up chromosomes. Mutations in the SMARCE1 gene can lead to a disruption in the normal regulation of gene expression, which can cause meningiomas to develop.

What is Familial Susceptibility?

Familial susceptibility means that certain genetic mutations can increase the risk of developing meningiomas. In the case of SMARCE1 gene meningioma, the mutation is inherited in an autosomal dominant pattern, which means that a person only needs to inherit one copy of the mutated gene from one parent to be at risk of developing the condition.

Symptoms of SMARCE1 Gene Meningioma

The symptoms of SMARCE1 gene meningioma are similar to those of other types of meningiomas and can include:

• Headaches
• Seizures
• Memory loss
• Difficulty concentrating
• Weakness or numbness in the limbs
• Vision problems

Diagnosis of SMARCE1 Gene Meningioma

SMARCE1 gene meningioma can be diagnosed through genetic testing, which can identify the mutation in the SMARCE1 gene. This testing is typically done using next-generation sequencing (NGS) technology, which can analyze large amounts of genetic data quickly and accurately.

NGS Genetic DNA Test Cost

The cost of NGS genetic DNA testing for SMARCE1 gene meningioma in India is approximately INR 20,000. This cost may vary depending on the specific testing facility and the extent of the testing that is required.

Conclusion

SMARCE1 gene meningioma is a rare form of meningioma that is caused by a genetic mutation in the SMARCE1 gene. Familial susceptibility can increase the risk of developing this condition, and symptoms can include headaches, seizures, memory loss, and weakness in the limbs. NGS genetic DNA testing can be used to diagnose SMARCE1 gene meningioma, and the cost of this testing in India is approximately INR 20,000. If you are experiencing symptoms of meningioma or have a family history of the condition, it is important to speak with a healthcare professional about the possibility of genetic testing.