Short Description

NGS genetic DNA test detecets for variant and mutation detection in SLC6A2 gene for Orthostatic intolerance

PreTest Information

Clinical History of Patient who is going for SLC6A2 Gene Orthostatic intolerance NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SLC6A2 Gene Orthostatic intolerance NGS Genetic DNA Test gene SLC6A2

Detail Description

SLC6A2 Gene Orthostatic Intolerance NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

Orthostatic intolerance (OI) is a condition that affects the ability of a person to maintain their blood pressure and heart rate when standing upright. It is a common problem that affects millions of people worldwide, and it can be caused by a variety of factors, including genetics. The SLC6A2 gene is one of the genes that have been associated with orthostatic intolerance, and testing for this gene can help diagnose the condition and provide targeted treatment options.

What is the SLC6A2 Gene?

The SLC6A2 gene codes for the norepinephrine transporter, which is responsible for the reuptake of norepinephrine, a neurotransmitter involved in the regulation of blood pressure and heart rate. Variations in this gene can affect the function of the norepinephrine transporter, leading to alterations in blood pressure and heart rate regulation that can contribute to orthostatic intolerance.

What are the Symptoms of Orthostatic Intolerance?

The symptoms of orthostatic intolerance can vary from person to person, but some of the most common include:

• Dizziness or lightheadedness when standing up
• Fainting or near-fainting episodes
• Heart palpitations or rapid heartbeat
• Shortness of breath
• Fatigue
• Headaches

How is Orthostatic Intolerance Diagnosed?

Diagnosing orthostatic intolerance typically involves a combination of medical history, physical examination, and specialized testing. One of the most useful tests for diagnosing orthostatic intolerance is the tilt table test, which involves monitoring a person's blood pressure and heart rate while they are tilted at different angles. Genetic testing for the SLC6A2 gene can also be helpful in diagnosing orthostatic intolerance, especially in cases where other causes have been ruled out.

What is NGS Genetic DNA Testing?

Next-generation sequencing (NGS) genetic testing is a powerful tool for identifying genetic variations that may contribute to orthostatic intolerance. This type of testing involves sequencing the entire genome or specific gene regions to identify variations that may be contributing to the condition. NGS testing is highly accurate and can provide a wealth of information about a person's genetic makeup, which can be used to develop targeted treatment plans.

What is the Cost of NGS Genetic DNA Testing for SLC6A2 Gene Orthostatic Intolerance?

The cost of NGS genetic DNA testing for the SLC6A2 gene can vary depending on the provider and the extent of testing performed. On average, the cost of this type of testing in India is around INR 20000. While this may seem expensive, the information gained from this type of testing can be invaluable in helping to diagnose and treat orthostatic intolerance.

Conclusion

Orthostatic intolerance is a common condition that can significantly impact a person's quality of life. Testing for the SLC6A2 gene using NGS genetic DNA testing can provide valuable insights into the underlying causes of the condition and help develop targeted treatment plans. While the cost of this testing may seem high, the benefits of accurate diagnosis and effective treatment far outweigh the expense.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SLC6A2 Gene Orthostatic intolerance NGS Genetic DNA Test