Short Description

NGS genetic DNA test detecets for variant and mutation detection in SDHB gene for Paragangliomas type 4

PreTest Information

Clinical History of Patient who is going for SDHB Gene Paragangliomas type 4 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with SDHB Gene Paragangliomas type 4 NGS Genetic DNA Test gene SDHB

Detail Description

SDHB Gene Paragangliomas type 4 NGS Genetic DNA Test: Symptoms, Diagnosis, and Cost

Paragangliomas are rare tumors that develop in the nervous system. They can occur in different parts of the body, such as the head, neck, chest, and abdomen. These tumors can be benign or malignant, and they can produce various symptoms depending on their location and size.

Paragangliomas are caused by genetic mutations that affect the production of certain proteins in the cells. One of the genes associated with paragangliomas is the SDHB gene, which encodes a protein that is involved in the energy production of the cells. Mutations in the SDHB gene can lead to the development of paragangliomas type 4, which are usually located in the abdomen.

Symptoms of SDHB Gene Paragangliomas type 4

The symptoms of SDHB gene paragangliomas type 4 can vary depending on the location and size of the tumor. Some of the common symptoms include:

• Abdominal pain or discomfort
• Nausea and vomiting
• High blood pressure
• Heart palpitations
• Headaches
• Anxiety
• Weight loss

These symptoms can also be caused by other conditions, so it's important to consult a doctor for an accurate diagnosis.

Diagnosis of SDHB Gene Paragangliomas type 4

The diagnosis of SDHB gene paragangliomas type 4 usually involves a combination of imaging tests, blood tests, and genetic testing. The imaging tests can include CT scans, MRI scans, and PET scans, which can help identify the location and size of the tumor. Blood tests can also be used to measure the levels of certain hormones that are produced by the tumor.

Genetic testing is also an important part of the diagnosis process, as it can help identify the presence of mutations in the SDHB gene. This can be done through a simple blood or saliva test, which can be sent to a laboratory for analysis.

SDHB Gene Paragangliomas type 4 NGS Genetic DNA Test Cost

The cost of SDHB gene paragangliomas type 4 NGS genetic DNA test can vary depending on the laboratory and location. In India, the cost of this test can range from INR 20,000 to INR 30,000. This test can be performed by DNA Labs India, which is a leading provider of genetic testing services in the country.

It's important to note that this test may not be covered by insurance, so it's important to check with your insurance provider before getting the test done.

Conclusion

SDHB gene paragangliomas type 4 is a rare condition that can cause various symptoms depending on the location and size of the tumor. Genetic testing can help identify the presence of mutations in the SDHB gene, which can help with the diagnosis and treatment of the condition. The cost of this test can vary, but it's an important investment in your health if you suspect you may have this condition.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SDHB Gene Paragangliomas type 4 NGS Genetic DNA Test