Short Description

RUNX1-RUNX1T1 (AML1- ETO) t(8;21) Qualitative is performed using Real Time PCR methodology. Sample that have to be given is Bone marrow / Peripheral blood (Transport immediately) in EDTA Vacutainer (2ml) for this test. You can expect results in 3-4 days

PreTest Information

RUNX1-RUNX1T1 (AML1- ETO) t(8;21) Qualitative can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Qualitative Test Cost and Diagnosis

Acute Myeloid Leukemia (AML) is a type of blood cancer that affects the bone marrow and blood cells. It is caused by the abnormal growth and division of myeloid cells in the bone marrow. RUNX1-RUNX1T1 (AML1-ETO) t(8;21) is a specific genetic mutation that is found in about 15-20% of AML cases. This mutation is caused by the translocation of two genes, RUNX1 and RUNX1T1, on chromosomes 8 and 21, respectively.

Symptoms of AML1-ETO t(8;21)

Some common symptoms of AML1-ETO t(8;21) include:

• Fever and chills
• Shortness of breath
• Fatigue
• Unexplained weight loss
• Bruising or bleeding easily
• Joint pain or swelling
• Enlarged spleen or liver

Diagnosis of AML1-ETO t(8;21)

AML1-ETO t(8;21) is diagnosed through a bone marrow biopsy and a genetic test. The bone marrow biopsy involves inserting a needle into the bone marrow to extract a small sample of cells for examination. The genetic test looks for the specific translocation of the RUNX1 and RUNX1T1 genes on chromosomes 8 and 21, respectively.

RUNX1-RUNX1T1 (AML1-ETO) t(8;21) Qualitative Test Cost

The cost of the RUNX1-RUNX1T1 (AML1-ETO) t(8;21) qualitative test in India is approximately INR 4500. The test can be performed at DNA Labs India, a leading diagnostic lab in the country.

Conclusion

AML1-ETO t(8;21) is a specific genetic mutation found in a subset of AML cases. The symptoms of this mutation are similar to those of AML in general, and diagnosis requires a bone marrow biopsy and genetic testing. The cost of the RUNX1-RUNX1T1 (AML1-ETO) t(8;21) qualitative test at DNA Labs India is approximately INR 4500.

Early diagnosis and treatment of AML1-ETO t(8;21) can improve the chances of a successful outcome, and it is important for individuals experiencing symptoms of AML to seek medical attention promptly.