Short Description

NGS genetic DNA test detecets for variant and mutation detection in PTPN11 gene for Leukemia, juvenile myelomonocytic

PreTest Information

Clinical History of Patient who is going for PTPN11 Gene Leukemia, juvenile myelomonocytic NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PTPN11 Gene Leukemia, juvenile myelomonocytic NGS Genetic DNA Test gene PTPN11

Detail Description

PTPN11 Gene Leukemia: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Leukemia is a type of cancer that affects the blood and bone marrow. It is caused by the abnormal growth of white blood cells in the body. Juvenile myelomonocytic leukemia (JMML) is a rare type of leukemia that usually affects children under the age of 4. It is caused by a mutation in the PTPN11 gene, which is involved in the regulation of cell growth and division.

PTPN11 Gene and JMML

The PTPN11 gene is located on chromosome 12 and encodes a protein called SHP-2. This protein is involved in the regulation of cell growth and division, as well as other cellular processes. Mutations in the PTPN11 gene have been found to be associated with a number of different diseases, including JMML.

JMML is a rare type of leukemia that usually affects children under the age of 4. It is characterized by the abnormal growth of white blood cells in the bone marrow and other parts of the body. Symptoms of JMML include:

• Anemia
• Frequent infections
• Bruising or bleeding easily
• Enlarged spleen or liver
• Swollen lymph nodes

Diagnosis of PTPN11 Gene Leukemia

Diagnosis of PTPN11 gene leukemia usually involves a combination of physical exams, blood tests, and bone marrow biopsies. Blood tests can reveal abnormal levels of white blood cells, red blood cells, and platelets. Bone marrow biopsies involve the removal of a small amount of bone marrow from the hipbone or breastbone and examining it under a microscope for signs of leukemia.

NGS Genetic DNA testing is a valuable tool for identifying mutations in the PTPN11 gene associated with JMML. This type of testing involves sequencing the entire genome to identify mutations that may be causing the disease. NGS Genetic DNA testing is highly accurate and can help doctors identify the specific mutations that are causing the disease.

Cost of NGS Genetic DNA Testing for PTPN11 Gene Leukemia

The cost of NGS Genetic DNA testing for PTPN11 gene leukemia in India is around INR 20,000. This cost may vary depending on the specific testing facility and the complexity of the test. It is important to discuss the cost of testing with your doctor or genetic counselor before undergoing testing.

Conclusion

PTPN11 gene leukemia is a rare type of leukemia that usually affects children under the age of 4. Symptoms of the disease include anemia, frequent infections, bruising or bleeding easily, enlarged spleen or liver, and swollen lymph nodes. Diagnosis of the disease usually involves physical exams, blood tests, and bone marrow biopsies. NGS Genetic DNA testing is a valuable tool for identifying mutations in the PTPN11 gene associated with JMML. The cost of NGS Genetic DNA testing for PTPN11 gene leukemia in India is around INR 20,000.

If you suspect that you or your child may have PTPN11 gene leukemia, it is important to speak with your doctor or genetic counselor about testing and treatment options.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for PTPN11 Gene Leukemia, juvenile myelomonocytic NGS Genetic DNA Test