Short Description

NGS genetic DNA test detecets for variant and mutation detection in PSEN1 gene for Pick disease

PreTest Information

Clinical History of Patient who is going for PSEN1 Gene Pick disease NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with PSEN1 Gene Pick disease

Detail Description

PSEN1 Gene Pick Disease NGS Genetic DNA Test Cost INR:20000 Symptoms Diagnosis

Pick disease is a rare, inherited neurological disorder that affects the brain. This disease is caused by mutations in the PSEN1 gene, which is responsible for producing a protein called presenilin-1.

Presenilin-1 is involved in the processing of a protein called amyloid precursor protein (APP), which is found in the brain. In people with Pick disease, mutations in the PSEN1 gene lead to the accumulation of abnormal proteins in the brain, which can damage brain cells and cause symptoms.

Symptoms of Pick Disease

The symptoms of Pick disease can vary from person to person, but they typically include:

• Difficulty with language and communication
• Changes in personality and behavior
• Loss of memory and other cognitive abilities
• Problems with movement and coordination

The symptoms of Pick disease usually begin in midlife, between the ages of 40 and 60. The disease tends to progress slowly over several years, with symptoms becoming more severe over time.

Diagnosis of Pick Disease

Diagnosing Pick disease can be challenging, as the symptoms can be similar to those of other neurological disorders. However, a diagnosis of Pick disease may be suspected if a person has a family history of the disease and shows symptoms such as language difficulties, behavioral changes, and cognitive decline.

Genetic testing can confirm a diagnosis of Pick disease. The most common genetic test used to diagnose Pick disease is next-generation sequencing (NGS), which can detect mutations in the PSEN1 gene. NGS is a type of genetic testing that can analyze multiple genes at once, making it a fast and efficient way to identify genetic mutations.

Cost of NGS Genetic DNA Test for Pick Disease

The cost of NGS genetic testing for Pick disease can vary depending on the testing provider and the specific test being performed. In India, the cost of NGS genetic testing for Pick disease is typically around INR 20,000.

Conclusion

Pick disease is a rare neurological disorder caused by mutations in the PSEN1 gene. Symptoms of the disease include language difficulties, behavioral changes, and cognitive decline. Genetic testing, such as NGS, can confirm a diagnosis of Pick disease. The cost of NGS genetic testing for Pick disease in India is typically around INR 20,000.

If you suspect that you or a loved one may have Pick disease, it is important to speak with a healthcare professional for proper diagnosis and treatment.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for PSEN1 Gene Pick disease NGS Genetic DNA Test