What is PSEN1 Gene Dementia?

PSEN1 Gene Dementia is a type of dementia that is caused by mutations in the PSEN1 gene. This gene is responsible for producing a protein that helps to break down amyloid beta, a protein that can accumulate in the brain and form plaques. When the PSEN1 gene is mutated, it can lead to an overproduction of amyloid beta, which can cause damage to brain cells and lead to dementia.

Frontotemporal NGS Genetic DNA Test

DNA Labs India offers a frontotemporal NGS Genetic DNA Test that can detect mutations in the PSEN1 gene. This test uses next-generation sequencing (NGS) technology to analyze the DNA sample and identify any genetic variants that may be associated with PSEN1 Gene Dementia.

The cost of the test is INR 20,000.

Symptoms and Diagnosis

The symptoms of PSEN1 Gene Dementia can vary depending on the individual and the stage of the disease. Common symptoms include:

• Memory loss
• Difficulty with language and communication
• Changes in personality and behavior
• Difficulty with movement and coordination

Diagnosing PSEN1 Gene Dementia can be challenging as the symptoms can be similar to other types of dementia. A diagnosis typically involves a physical exam, neurological exam, and cognitive tests. Genetic testing can also be used to confirm a diagnosis and identify any underlying genetic mutations.