Short Description

The prothrombin G20210A mutation is the second most common inherited predisposition to hypercoagulability. Heterozygous prothrombin G20210A mutation is associated with a 2 to 6 fold increased lifetime relative risk of VTE. This risk is further increased in combination with pregnancy and OCP use.

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

PROTHROMBIN GENE MUTATION ANALYSIS Test: Symptoms, Diagnosis and Cost in India

Prothrombin gene mutation analysis is a test that helps in the identification of a genetic mutation known as prothrombin gene mutation. This genetic mutation increases the risk of developing blood clots, which can lead to severe health complications such as deep vein thrombosis, pulmonary embolism, and stroke.

Symptoms of Prothrombin Gene Mutation

Prothrombin gene mutation is a genetic disorder that may not show any symptoms in most cases. However, in some people, the mutation can lead to an increased risk of developing blood clots. The symptoms of blood clots may include:

• Pain or swelling in the legs
• Redness or discoloration of the skin
• Shortness of breath
• Chest pain or discomfort
• Dizziness or fainting

Diagnosis of Prothrombin Gene Mutation

Prothrombin gene mutation analysis is a simple blood test that can be performed in a laboratory. The test identifies the presence of a specific genetic mutation in the prothrombin gene. If the test results show the presence of the mutation, it means that the individual has an increased risk of developing blood clots.

Doctors may recommend prothrombin gene mutation analysis in individuals with a family history of blood clots, a personal history of blood clots, or in those who have an unexplained history of recurrent miscarriages.

Cost of Prothrombin Gene Mutation Analysis Test in India

The cost of prothrombin gene mutation analysis test in India varies depending on the location and the laboratory where the test is performed. On average, the cost of the test in India ranges from INR 4500 to INR 6000.

It is essential to note that the cost of the test may vary depending on the additional tests performed along with prothrombin gene mutation analysis. It is always advisable to consult with a doctor or a healthcare professional to understand the cost and the necessity of the test.

Conclusion

Prothrombin gene mutation analysis is a simple blood test that can help identify the presence of a genetic mutation that increases the risk of developing blood clots. The test is recommended for individuals with a family or personal history of blood clots or those who have recurrent miscarriages. The cost of the test in India ranges from INR 4500 to INR 6000 and may vary depending on the location and the laboratory where the test is performed.

If you are concerned about your risk of developing blood clots or have a family history of blood clots, it is always advisable to consult with a doctor or a healthcare professional to understand the necessity of prothrombin gene mutation analysis and other tests.

The prothrombin G20210A mutation is the second most common inherited predisposition to hypercoagulability. Heterozygous prothrombin G20210A mutation is associated with a 2 to 6 fold increased lifetime relative risk of VTE. This risk is further increased in combination with pregnancy and OCP use.