Short Description

NGS genetic DNA test detecets for variant and mutation detection in PRNP gene for Huntington disease-like type 1

PreTest Information

Clinical History of Patient who is going for PRNP Gene Huntington disease-like type 1 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with PRNP Gene Huntington disease-like type 1

Detail Description

PRNP Gene Huntington disease-like type 1 NGS Genetic DNA Test - Symptoms, Diagnosis, and Cost

PRNP gene Huntington disease-like type 1 is a rare genetic disorder that affects the nervous system. It is caused by mutations in the PRNP gene, which provides instructions for making a protein called prion protein. This protein is found throughout the body but is most abundant in the brain. When mutated, it can cause the protein to fold incorrectly and form clumps in the brain, leading to nerve cell damage and ultimately, the symptoms of the disease.

Symptoms

The symptoms of PRNP gene Huntington disease-like type 1 can vary widely from person to person, but some common symptoms include:

• Muscle stiffness and rigidity
• Tremors
• Difficulty with coordination and balance
• Changes in behavior and personality
• Memory loss and confusion
• Difficulty speaking or swallowing

These symptoms can start at any age, but most people with PRNP gene Huntington disease-like type 1 develop symptoms in their 30s or 40s.

Diagnosis

Diagnosing PRNP gene Huntington disease-like type 1 can be challenging because it is such a rare disorder. Doctors will typically begin by performing a physical exam and taking a detailed medical history to look for any signs or symptoms of the disease. They may also order a series of tests, including:

• Neurological exam to assess muscle tone, reflexes, and coordination
• MRI or CT scan to look for changes in the brain
• Genetic testing to look for mutations in the PRNP gene

Genetic testing is the most accurate way to diagnose PRNP gene Huntington disease-like type 1. It involves analyzing a sample of the patient's DNA to look for mutations in the PRNP gene. This can be done using a variety of techniques, but next-generation sequencing (NGS) is the most advanced and accurate method available.

NGS Genetic DNA Test Cost

The cost of an NGS genetic DNA test for PRNP gene Huntington disease-like type 1 can vary depending on the provider and location. In India, the average cost is around INR 20,000. It is important to note that this is just the cost of the test itself and does not include any additional fees that may be associated with the testing process, such as consultation fees or sample collection fees.

Conclusion

PRNP gene Huntington disease-like type 1 is a rare genetic disorder that can cause a range of symptoms affecting the nervous system. Diagnosis can be challenging, but genetic testing using NGS is the most accurate method available. If you are experiencing symptoms or have a family history of the disease, it is important to talk to your doctor about the possibility of genetic testing and the associated costs.

At DNA Labs India, we offer NGS genetic DNA testing for PRNP gene Huntington disease-like type 1 at an affordable cost. Our team of experts uses the latest technology to ensure accurate and reliable results. Contact us today to learn more about our testing services.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for PRNP Gene Huntington disease-like type 1 NGS Genetic DNA Test