Short Description

NGS genetic DNA test detecets for variant and mutation detection in PRNP gene for Gerstmann-Straussler disease

PreTest Information

Clinical History of Patient who is going for PRNP Gene Gerstmann-Straussler disease NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with PRNP Gene Gerstmann-Straussler disease

Detail Description

PRNP Gene Gerstmann-Straussler disease NGS Genetic DNA Test: Symptoms, Diagnosis, and Cost

Gerstmann-Straussler disease (GSD) is a rare genetic disorder that affects the nervous system. It belongs to a group of disorders called prion diseases, which are caused by abnormal proteins called prions that accumulate in the brain and cause damage to nerve cells. GSD is caused by mutations in the PRNP gene, which provides instructions for making a protein called prion protein.

Symptoms of GSD

The symptoms of GSD can vary depending on the type of mutation and the age of onset. The most common symptoms of GSD include:

• Difficulty with coordination and balance
• Loss of muscle control and muscle stiffness
• Weakness and numbness in the limbs
• Changes in behavior and personality
• Memory problems and dementia

Diagnosis of GSD

GSD can be difficult to diagnose because it is a rare disease and the symptoms can be similar to other neurological disorders. Diagnosis usually involves a combination of clinical evaluation, genetic testing, and imaging studies.

Genetic testing is the most reliable way to diagnose GSD. Next-generation sequencing (NGS) is a powerful tool that can analyze multiple genes at once and identify mutations that cause GSD. NGS can detect mutations in the PRNP gene with high accuracy and sensitivity.

The Cost of GSD NGS Genetic DNA Test

The cost of GSD NGS genetic DNA test in India is around INR 20,000. This cost includes the genetic testing, counseling, and interpretation of the test results. The price may vary depending on the laboratory and the specific test ordered.

Conclusion

GSD is a rare genetic disorder that can cause a wide range of neurological symptoms. Genetic testing using NGS is the most reliable way to diagnose GSD. The cost of GSD NGS genetic DNA test in India is around INR 20,000. Early diagnosis and treatment can help improve the quality of life for people with GSD and their families.

If you or a loved one is experiencing symptoms of GSD, it is important to seek medical attention and consider genetic testing to determine the cause of the symptoms. DNA Labs India provides reliable and accurate genetic testing services for GSD and other genetic disorders.

Contact DNA Labs India today to learn more about our genetic testing services.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for PRNP Gene Gerstmann-Straussler disease NGS Genetic DNA Test