Short Description

NGS genetic DNA test detecets for variant and mutation detection in PRNP gene for Fatal familial imsomnia

PreTest Information

Clinical History of Patient who is going for PRNP Gene Fatal familial imsomnia NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with PRNP Gene Fatal familial imsomnia

Detail Description

PRNP Gene: Understanding Fatal Familial Insomnia through NGS Genetic DNA Test

Fatal Familial Insomnia (FFI) is a rare genetic disease that affects the sleep cycle of an individual. It is caused by mutations in the PRNP gene that leads to the build-up of abnormal prion proteins in the brain. FFI is a progressive disease that results in the loss of sleep and eventually leads to death. The diagnosis of FFI can be made through a Next-Generation Sequencing (NGS) Genetic DNA Test.

Symptoms of FFI

The symptoms of FFI usually start to appear in midlife, around the age of 40 to 50 years. The first symptoms of FFI are usually related to sleep, which may include:

• Difficulty falling asleep
• Difficulty staying asleep
• Excessive daytime sleepiness
• Insomnia

As the disease progresses, the symptoms may become more severe and may include:

• Hallucinations
• Memory loss
• Difficulty swallowing
• Involuntary movements
• Loss of coordination
• Coma

Diagnosis of FFI

The diagnosis of FFI can be made through a genetic test that looks for mutations in the PRNP gene. The NGS Genetic DNA Test is a highly advanced test that uses next-generation sequencing technology to analyze the entire PRNP gene and identify any mutations that may be present. The test can also be used to identify other genetic mutations that may be associated with FFI.

The NGS Genetic DNA Test is a simple and painless procedure that involves taking a small sample of blood or saliva. The sample is then sent to a laboratory for analysis. The results of the test are usually available within a few weeks.

Cost of NGS Genetic DNA Test

The cost of the NGS Genetic DNA Test for FFI in India is around INR 20,000. The cost may vary depending on the laboratory and location.

Conclusion

FFI is a rare and fatal genetic disease that affects the sleep cycle of an individual. The diagnosis of FFI can be made through a Next-Generation Sequencing (NGS) Genetic DNA Test. The test is a simple and painless procedure that involves taking a small sample of blood or saliva. The cost of the NGS Genetic DNA Test for FFI in India is around INR 20,000. If you suspect that you or someone you know may have FFI, it is important to seek medical attention immediately.

At DNA Labs India, we offer a wide range of genetic tests, including the NGS Genetic DNA Test for FFI. Our tests are conducted in state-of-the-art laboratories and are performed by highly trained professionals. Contact us today to learn more about our genetic testing services.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for PRNP Gene Fatal familial imsomnia NGS Genetic DNA Test