Short Description

Prenatal Hemophilia A Common Mutation Screening (Factor VIII Intron 22 and Intron 1 Inversion analysis) is performed using End Point PCR methodology. Sample that have to be given is Peripheral blood/Amniotic Fluid/ Chorionic villi/ Cord blood in Sterile container/ Sterile Normal Saline Container/ EDTA Vacutainer (2ml) for this test. You can expect results in 10-11 days

PreTest Information

Prenatal Hemophilia A Common Mutation Screening (Factor VIII Intron 22 and Intron 1 Inversion analysis) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad.

Detail Description

Prenatal Hemophilia A Common Mutation Screening (Factor VIII Intron 22 and Intron 1 Inversion Analysis) Cost INR: 15000 Symptoms Diagnosis

Hemophilia A is a genetic disorder that affects blood clotting. It is caused by a deficiency of the clotting factor VIII. Hemophilia A is inherited in an X-linked recessive pattern, meaning it is more common in males than females. Prenatal screening for hemophilia A is available to pregnant women who have a family history of the disorder or who carry the hemophilia A gene. One common method of prenatal screening is Factor VIII Intron 22 and Intron 1 Inversion analysis.

Symptoms of Hemophilia A

The symptoms of hemophilia A vary depending on the severity of the condition. Mild cases may not show any symptoms until there is an injury or surgery, while severe cases may show symptoms from infancy. Symptoms of hemophilia A include:

• Excessive bleeding from cuts and injuries
• Bruising easily
• Bleeding into muscles and joints, causing pain and stiffness
• Bleeding into the brain or other organs, which can be life-threatening

Diagnosis of Hemophilia A

Hemophilia A is diagnosed through blood tests that measure the amount of clotting factor VIII in the blood. Genetic testing can also be done to confirm a diagnosis and identify the specific mutation causing the disorder.

Prenatal Hemophilia A Common Mutation Screening

Prenatal screening for hemophilia A can be done through Factor VIII Intron 22 and Intron 1 Inversion analysis. This test looks for two common mutations that cause hemophilia A. It is a non-invasive test that can be done as early as 10 weeks into a pregnancy through a blood sample taken from the mother.

Cost of Prenatal Hemophilia A Common Mutation Screening

The cost of prenatal hemophilia A common mutation screening (Factor VIII Intron 22 and Intron 1 Inversion analysis) is INR 15000 in India. This cost may vary depending on the lab and location.

Conclusion

Prenatal screening for hemophilia A is available to pregnant women with a family history of the disorder or who carry the hemophilia A gene. Factor VIII Intron 22 and Intron 1 Inversion analysis is a common method of prenatal screening for hemophilia A that is non-invasive and can be done as early as 10 weeks into a pregnancy. The cost of this screening is INR 15000 in India.

It is important for pregnant women to discuss prenatal screening options with their healthcare provider to determine if they are at risk for hemophilia A and if prenatal screening is necessary.

For more information on prenatal hemophilia A common mutation screening, contact DNA Labs India.