Short Description

NGS genetic DNA test detecets for variant and mutation detection in PPP1R17 gene for Hypercholesterolemia, susceptibility to

PreTest Information

Clinical History of Patient who is going for PPP1R17 Gene Hypercholesterolemia, susceptibility to NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hypercholesterolemia, susceptibility to

Detail Description

PPP1R17 Gene Hypercholesterolemia: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Hypercholesterolemia is a medical condition characterized by high levels of cholesterol in the blood. It is a major risk factor for cardiovascular disease, which is the leading cause of death worldwide. Genetic factors play a significant role in hypercholesterolemia, and one such gene is PPP1R17. In this blog, we will discuss PPP1R17 Gene Hypercholesterolemia, its symptoms, diagnosis, and the cost of NGS Genetic DNA Test in India.

PPP1R17 Gene Hypercholesterolemia: What is it?

PPP1R17 is a gene that codes for a protein called Inhibitor-1. This protein regulates the activity of an enzyme called Protein Phosphatase 1 (PP1), which is involved in the metabolism of lipids, including cholesterol. Mutations in the PPP1R17 gene can lead to hypercholesterolemia, a condition where there is an excess of cholesterol in the blood.

PPP1R17 Gene Hypercholesterolemia: Symptoms

Hypercholesterolemia does not typically cause any symptoms. However, over time, the excess cholesterol can lead to the formation of plaques in the arteries, which can cause atherosclerosis. Atherosclerosis can lead to a range of symptoms, including:

• Chest pain (angina)
• Shortness of breath
• Numbness or weakness in the legs
• Slurred speech or difficulty speaking
• Peripheral artery disease (PAD)
• Heart attack
• Stroke

PPP1R17 Gene Hypercholesterolemia: Diagnosis

Hypercholesterolemia is typically diagnosed through a blood test that measures the levels of cholesterol in the blood. A total cholesterol level of 240 milligrams per deciliter (mg/dL) or higher is considered high. However, genetic testing can also be used to diagnose hypercholesterolemia caused by mutations in the PPP1R17 gene. Next-generation sequencing (NGS) genetic tests can detect mutations in the PPP1R17 gene with high accuracy.

PPP1R17 Gene Hypercholesterolemia: NGS Genetic DNA Test Cost in India

The cost of NGS Genetic DNA Test in India for PPP1R17 Gene Hypercholesterolemia can vary depending on the laboratory and the specific test being performed. However, on average, the cost of NGS Genetic DNA Test in India for PPP1R17 Gene Hypercholesterolemia is around INR 20,000.

Conclusion

PPP1R17 Gene Hypercholesterolemia is a genetic condition that can lead to high levels of cholesterol in the blood, which is a major risk factor for cardiovascular disease. Symptoms of hypercholesterolemia may not be noticeable, but over time, it can lead to serious health problems such as heart attack and stroke. Diagnosis of hypercholesterolemia can be done through a blood test or genetic testing, and the cost of NGS Genetic DNA Test in India for PPP1R17 Gene Hypercholesterolemia is around INR 20,000. If you suspect that you may have hypercholesterolemia, it is important to consult with a healthcare professional for proper diagnosis and treatment.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for PPP1R17 Gene Hypercholesterolemia, susceptibility to NGS Genetic DNA Test