Short Description

Screens for genetic susceptibility for venous thromboembolism (VTE) or myocardial infarction (MI) in individuals with a personal or family history of thrombotic events and Aids risk/benefit assessment for preventive or therapeutic interventions for VTE or MI.

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING Test - Symptoms, Diagnosis, and Cost

DNA Labs India offers the PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING test, which is a genetic test that determines an individual's risk of developing blood clots and related conditions. This test is particularly useful for individuals who have a family history of blood clots, as well as those who have experienced blood clots themselves.

Symptoms and Diagnosis

Blood clots can cause a range of symptoms, depending on where they occur in the body. Some of the most common symptoms of blood clots include:

• Pain or swelling in the affected area
• Redness or warmth in the affected area
• Shortness of breath
• Chest pain
• Dizziness or fainting
• Headaches or vision changes

If you are experiencing any of these symptoms, it is important to seek medical attention right away. Your doctor may perform a physical exam and order diagnostic tests, such as an ultrasound or CT scan, to determine if you have a blood clot.

PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING Test

The PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING test is a simple and non-invasive genetic test that can be performed using a sample of your blood or saliva. The test looks for variations in the SERPINE1 gene, which produces a protein called plasminogen activator inhibitor-1 (PAI-1).

PAI-1 is a natural inhibitor of blood clotting, and variations in the SERPINE1 gene can affect the amount of PAI-1 that is produced by the body. Individuals with the 4G/4G genotype have been shown to produce higher levels of PAI-1, which can increase their risk of developing blood clots.

The PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING test can help identify individuals who are at an increased risk of developing blood clots, allowing them to take preventative measures to reduce their risk. This may include lifestyle changes, such as quitting smoking or losing weight, as well as medications that can help prevent blood clots.

Test Cost

The cost of the PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING test at DNA Labs India is INR 18,000. This includes the cost of the test itself, as well as any necessary consultations with a genetic counselor or other healthcare professional.

While the cost of genetic testing may seem high, it is important to remember that this test can provide valuable information about your health and help you make informed decisions about your future. Additionally, many insurance companies now cover the cost of genetic testing for individuals who are at an increased risk of developing certain conditions.

Conclusion

If you have a family history of blood clots or have experienced blood clots yourself, the PLASMINOGEN ACTIVATOR INHIBITOR-1/SERPINE-1 4G/5G GENOTYPING test may be a valuable tool for assessing your risk and taking preventative measures. Talk to your healthcare provider or a genetic counselor to learn more about this test and whether it may be right for you.

Screens for genetic susceptibility for venous thromboembolism (VTE) or myocardial infarction (MI) in individuals with a personal or family history of thrombotic events and Aids risk/benefit assessment for preventive or therapeutic interventions for VTE or MI.