Short Description

Procollagen type III amino terminal propeptide (PIIINP) has been used in assessment of liver fibrosis, as it is a marker of early fibrogenesis and inflammation._x000D_ Methotrexate (MTx) is a widely used drug for the treatment of Psoriasis and other dermatological conditions. MTx has been recognized to be hepatotoxic which limits itƒ??s therapeutic use. Thus, monitoring of liver for structural and functional damage is recommended before and during treatment with MTx. PIIINP test can be used to assess MTx induced liver toxicity, especially in high-risk individuals like patients with Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease, excessive alcohol consumption and Chronic Hepatitis B & C. This test has a sensitivity of 77% and specificity of 92% in assessment of liver toxicity in MTx treated patients with Psoriasis.

PreTest Information

Overnight fasting is preferred.

Detail Description

PIIINP (PROCOLLAGEN TYPE III AMINO TERMINAL PROPEPTIDE) Test Cost INR:5500 Symptoms Diagnosis

PIIINP (procollagen type III amino terminal propeptide) is a protein that is produced when the body forms collagen, which is a major component of the connective tissue in our body. The PIIINP test is a blood test that measures the level of this protein in the blood. The test is used to diagnose liver fibrosis, which is a condition where the liver becomes damaged and scarred due to various reasons like excessive alcohol consumption, viral infections, or non-alcoholic fatty liver disease.

Symptoms of Liver Fibrosis

The early stages of liver fibrosis may not show any symptoms. However, as the condition progresses, the following symptoms may appear:

• Jaundice (yellowing of the skin and eyes)
• Abdominal pain and swelling
• Fatigue and weakness
• Nausea and vomiting
• Loss of appetite

Diagnosis of Liver Fibrosis

There are several ways to diagnose liver fibrosis, including:

• Blood tests
• Imaging tests (ultrasound, MRI, CT scan)
• Liver biopsy
• FibroScan (a non-invasive test that uses ultrasound waves to measure liver stiffness)
• PIIINP test

PIIINP Test Cost in India

The PIIINP test cost in India varies depending on the location and the laboratory. However, the average cost of the test is around INR 5500.

Conclusion

The PIIINP test is a useful tool in diagnosing liver fibrosis, which is a serious condition that can lead to liver failure if left untreated. If you are experiencing any symptoms of liver fibrosis, it is important to consult a doctor and get diagnosed as early as possible. With early diagnosis and proper treatment, liver fibrosis can be managed effectively.

At DNA Labs India, we offer the PIIINP test at an affordable cost. Our laboratory is equipped with the latest technology and our team of experts are dedicated to providing accurate and timely results. Contact us today to schedule your PIIINP test.

Procollagen type III amino terminal propeptide (PIIINP) has been used in assessment of liver fibrosis, as it is a marker of early fibrogenesis and inflammation. Methotrexate (MTx) is a widely used drug for the treatment of Psoriasis and other dermatological conditions. MTx has been recognized to be hepatotoxic which limits itƒ??s therapeutic use. Thus, monitoring of liver for structural and functional damage is recommended before and during treatment with MTx. PIIINP test can be used to assess MTx induced liver toxicity, especially in high-risk individuals like patients with Metabolic Syndrome, Non-Alcoholic Fatty Liver Disease, excessive alcohol consumption and Chronic Hepatitis B & C. This test has a sensitivity of 77% and specificity of 92% in assessment of liver toxicity in MTx treated patients with Psoriasis.