Short Description

NGS genetic DNA test detecets for variant and mutation detection in PDX1 gene for Maturity-onset diabetes of the young type 4

PreTest Information

Clinical History of Patient who is going for PDX1 Gene Maturity-onset diabetes of the young type 4 NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Maturity-onset diabetes of the young type 4

Detail Description

PDX1 Gene Maturity-onset diabetes of the young type 4 NGS Genetic DNA Test

Maturity-onset diabetes of the young (MODY) is a type of diabetes that is caused by a mutation in a single gene. There are several different types of MODY, and each type is caused by a mutation in a different gene. MODY type 4 is caused by a mutation in the PDX1 gene.

The PDX1 gene provides instructions for making a protein called pancreatic and duodenal homeobox 1. This protein plays a critical role in the development and function of the pancreas, which is the organ that produces insulin. Insulin is a hormone that regulates blood sugar levels. People with MODY type 4 have a mutation in the PDX1 gene that reduces the amount of functional protein that is produced. This leads to a decrease in the amount of insulin that is produced, which can result in high blood sugar levels and the symptoms of diabetes.

Symptoms of MODY type 4

The symptoms of MODY type 4 are similar to those of other types of diabetes. They include:

• Increased thirst
• Increased urination
• Increased hunger
• Fatigue
• Blurred vision

These symptoms can develop slowly over time and may not be noticeable at first. If you are experiencing any of these symptoms, it is important to see a doctor for a diagnosis.

Diagnosis of MODY type 4

Diagnosis of MODY type 4 can be difficult because it is a rare form of diabetes. It is usually diagnosed in people who have a family history of diabetes that is diagnosed at a young age (under 25). A genetic test can be used to confirm the diagnosis. The test looks for mutations in the PDX1 gene. If a mutation is found, the diagnosis of MODY type 4 is confirmed.

NGS Genetic DNA Test for MODY type 4

The NGS Genetic DNA Test for MODY type 4 looks for mutations in the PDX1 gene. The test is performed using a small sample of blood or saliva. The sample is sent to a laboratory for analysis. The cost of the test is INR 20,000.

If you have a family history of diabetes that is diagnosed at a young age, or if you are experiencing symptoms of diabetes, it is important to talk to your doctor about getting tested for MODY type 4. Early diagnosis and treatment can help prevent complications and improve outcomes.

Conclusion

MODY type 4 is a rare form of diabetes that is caused by a mutation in the PDX1 gene. The symptoms of MODY type 4 are similar to those of other types of diabetes, and diagnosis can be difficult. The NGS Genetic DNA Test for MODY type 4 can be used to confirm the diagnosis. If you have a family history of diabetes or are experiencing symptoms of diabetes, talk to your doctor about getting tested for MODY type 4.

Early diagnosis and treatment can help prevent complications and improve outcomes. The cost of the test is INR 20,000.

Contact DNA Labs India to schedule an appointment for the NGS Genetic DNA Test for MODY type 4.