Short Description

NGS genetic DNA test detecets for variant and mutation detection in PDGFRB gene for Myeloproliferative disorder, chronic, with eosinophilia

PreTest Information

Clinical History of Patient who is going for PDGFRB Gene Myeloproliferative disorder, chronic, with eosinophilia NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PDGFRB Gene Myeloproliferative disorder, chronic, with eosinophilia NGS Genetic DNA Test gene PDGFRB

Detail Description

PDGFRB Gene Myeloproliferative Disorder, Chronic, with Eosinophilia NGS Genetic DNA Test

Myeloproliferative disorder, chronic, with eosinophilia (MPE) is a rare blood disorder in which there is an overproduction of white blood cells, specifically eosinophils. This disorder is caused by a genetic mutation in the PDGFRB gene. The PDGFRB gene provides instructions for making a protein that is involved in cell growth and division. When this gene mutates, it can lead to the overproduction of eosinophils and the development of MPE.

NGS (Next-Generation Sequencing) is a genetic test that can detect mutations in the PDGFRB gene. This test is done using a sample of blood or bone marrow. The cost of the NGS genetic DNA test for PDGFRB gene MPE in India is INR 20,000.

Symptoms of PDGFRB Gene MPE

The symptoms of PDGFRB gene MPE can vary from person to person. Some common symptoms of MPE include:

• Fever
• Fatigue
• Weakness
• Weight loss
• Night sweats
• Shortness of breath
• Chest pain
• Pain or swelling in the abdomen
• Enlarged liver or spleen
• Itching
• Swollen lymph nodes

Diagnosis of PDGFRB Gene MPE

Diagnosis of PDGFRB gene MPE can be done through a blood test or bone marrow biopsy. In a blood test, the number of eosinophils in the blood is measured. In a bone marrow biopsy, a sample of bone marrow is taken and examined under a microscope to look for abnormalities in the blood cells. Genetic testing can also be done to detect mutations in the PDGFRB gene.

Conclusion

PDGFRB gene MPE is a rare blood disorder that can cause a variety of symptoms. NGS genetic DNA testing can be used to detect mutations in the PDGFRB gene, which can aid in the diagnosis and treatment of this disorder. If you are experiencing symptoms of MPE, it is important to speak with a healthcare provider and consider genetic testing.

At DNA Labs India, we offer NGS genetic DNA testing for PDGFRB gene MPE at an affordable cost of INR 20,000. Our state-of-the-art laboratory and experienced team of geneticists ensure accurate and reliable results. Contact us today to learn more about our genetic testing services.