Short Description

This test is primarily used to evaluate the percentage of granulocytes in blood which express CD55, CD14, CD24 & CD59 and those which do not express them. These antigens are absent on the hemopoietic cells of patients suffering from PNH.

PreTest Information

Give brief clinical history.

Detail Description

PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) CONFIRMATORY TEST - Test cost INR:8500 symptoms diagnosis

Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare but serious blood disorder that affects the red blood cells, causing them to break down prematurely. This can lead to a range of symptoms, including fatigue, weakness, dark urine, and abdominal pain. If left untreated, PNH can also cause life-threatening complications, such as blood clots and organ damage.

Symptoms of PNH

The symptoms of PNH can vary from person to person and may not always be present. Some of the most common symptoms include:

• Fatigue and weakness
• Shortness of breath
• Dark urine
• Abdominal pain
• Headaches
• Difficulty swallowing
• Jaundice (yellowing of the skin and eyes)

Diagnosis of PNH

The diagnosis of PNH begins with a thorough physical examination and medical history review. Your doctor may also perform blood tests to look for signs of anemia (low red blood cell count) and other abnormalities. If PNH is suspected, your doctor may recommend a confirmatory test, such as:

• Flow cytometry: This test looks for specific proteins on the surface of red blood cells that are missing or abnormal in people with PNH.
• Ham's test: This test involves exposing red blood cells to a chemical that causes them to break down more easily. People with PNH will show increased sensitivity to this chemical.

PNH Confirmatory Test Cost

The cost of PNH confirmatory tests can vary depending on the location and type of test performed. In India, the cost of a flow cytometry test for PNH is typically around INR 8500.

Conclusion

If you are experiencing symptoms of PNH or have been diagnosed with the condition, it is important to seek treatment as soon as possible. With proper management and care, many people with PNH are able to live healthy and active lives. Talk to your healthcare provider about your options for testing and treatment.

At DNA Labs India, we offer reliable and accurate PNH confirmatory tests at an affordable cost. Contact us today to learn more.

This test is primarily used to evaluate the percentage of granulocytes in blood which express CD55, CD14, CD24 & CD59 and those which do not express them. These antigens are absent on the hemopoietic cells of patients suffering from PNH.