Short Description

NGS genetic DNA test detecets for variant and mutation detection in PALB2 gene for Breast cancer, susceptibility to

PreTest Information

Clinical History of Patient who is going for PALB2 Gene Breast cancer, susceptibility to NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with PALB2 Gene Breast cancer, susceptibility to NGS Genetic DNA Test gene PALB2

Detail Description

PALB2 Gene Breast Cancer: Susceptibility to NGS Genetic DNA Test Cost INR 20,000

Breast cancer is one of the most common types of cancer that affects women across the world. It is estimated that around 1 in 8 women will develop breast cancer at some point in their lives. While there are several factors that contribute to the development of breast cancer, genetics plays a significant role. Inherited mutations in certain genes, such as the PALB2 gene, can increase a woman's risk of developing breast cancer.

What is the PALB2 gene?

The PALB2 (Partner and Localizer of BRCA2) gene is a tumor suppressor gene that helps prevent the development of cancer. It works by repairing damaged DNA and preventing the formation of abnormal cells. However, mutations in the PALB2 gene can disrupt its normal function, leading to an increased risk of breast cancer.

Susceptibility to Breast Cancer

Women who inherit a PALB2 mutation have a significantly increased risk of developing breast cancer. In fact, studies have shown that women with a PALB2 mutation have a 35-58% lifetime risk of developing breast cancer. Additionally, women with a PALB2 mutation have an increased risk of developing ovarian cancer.

Symptoms and Diagnosis

Like most types of cancer, breast cancer often does not produce symptoms in its early stages. As the cancer progresses, symptoms may include a lump or swelling in the breast, changes in the shape or size of the breast, nipple discharge, and skin changes around the breast or nipple. If you experience any of these symptoms, it is important to see a doctor as soon as possible.

To diagnose breast cancer, your doctor will perform a physical examination and may order imaging tests such as mammography, ultrasound, or MRI. A biopsy may also be performed to confirm the diagnosis.

NGS Genetic DNA Test Cost INR 20,000

Next-generation sequencing (NGS) is a powerful technology that allows for the rapid and accurate sequencing of DNA. NGS can be used to identify mutations in genes such as PALB2 that increase a woman's risk of developing breast cancer. DNA Labs India offers an NGS genetic DNA test for breast cancer susceptibility that costs INR 20,000.

Conclusion

If you have a family history of breast cancer or are concerned about your risk, it is important to talk to your doctor about genetic testing. Identifying mutations in genes such as PALB2 can help you make informed decisions about your health and take steps to reduce your risk of developing breast cancer. The NGS genetic DNA test offered by DNA Labs India is a powerful tool for identifying these mutations and can provide valuable information about your risk of developing breast cancer.