Short Description

Juvenile Myelomonocytic Leukemia (JMML) is a rare, aggressive myeloproliferative/myelodysplastic disorder of infancy and childhood that is manifest as increased infiltration of the peripheral blood, bone marrow, and viscera by abnormal myelomonocytic cells.The sequencing of genes for JMML helps in making diagnosis, and also for prognostication and therapeutics decision making.

PreTest Information

Duly filled NGS Test Requisition Form (Form 40) is mandatory.

Detail Description

ONCOMINE JUVENILE MYELOMONOCYTIC LEUKEMIA (JMML) PANEL Test Cost and Diagnosis

Juvenile Myelomonocytic Leukemia (JMML) is a rare type of childhood leukemia that affects children under the age of 4. It is a type of myeloproliferative disorder, where the bone marrow produces too many immature white blood cells. The symptoms of JMML are very similar to other types of leukemia, which makes it difficult to diagnose. However, with the help of the Oncomine JMML Panel Test, doctors can quickly and accurately diagnose JMML.

What is the Oncomine JMML Panel Test?

The Oncomine JMML Panel Test is a genetic test that analyzes the DNA of a patient to identify mutations that are associated with JMML. The test uses next-generation sequencing technology to analyze 6 genes that are commonly associated with JMML. These genes include:

• NRAS
• KRAS
• PTPN11
• CBL
• SOS1
• BRAF

The test is performed on a blood or bone marrow sample, and the results are typically available within 10-14 days.

What are the Symptoms of JMML?

The symptoms of JMML are very similar to other types of leukemia and can include:

• Fever
• Fatigue
• Pallor
• Bruising or bleeding easily
• Enlarged spleen or liver
• Joint pain or swelling
• Frequent infections

It is important to note that not all children with JMML will experience all of these symptoms, and some children may not experience any symptoms at all.

How is JMML Diagnosed?

Diagnosing JMML can be difficult because the symptoms are very similar to other types of leukemia. However, doctors will typically perform a physical exam and blood tests to look for abnormalities in the blood cells. If abnormalities are found, a bone marrow biopsy may be performed to confirm the diagnosis.

The Oncomine JMML Panel Test can also be used to diagnose JMML by identifying mutations in the genes associated with the disease.

What is the Cost of the Oncomine JMML Panel Test?

The cost of the Oncomine JMML Panel Test in India is INR 40,950. This cost may vary depending on the location and the lab where the test is performed.

Conclusion

The Oncomine JMML Panel Test is a valuable tool for diagnosing JMML in children. With its ability to quickly and accurately identify mutations associated with the disease, doctors can provide early and effective treatment to improve patient outcomes. If you suspect that your child may have JMML, it is important to speak with a doctor as soon as possible to get an accurate diagnosis and begin treatment.

At DNA Labs India, we offer a wide range of genetic testing services, including the Oncomine JMML Panel Test. Contact us today to learn more about our services and how we can help you and your family.

Juvenile Myelomonocytic Leukemia (JMML) is a rare, aggressive myeloproliferative/myelodysplastic disorder of infancy and childhood that is manifest as increased infiltration of the peripheral blood, bone marrow, and viscera by abnormal myelomonocytic cells.The sequencing of genes for JMML helps in making diagnosis, and also for prognostication and therapeutics decision making.