Short Description

Isoelectric focusing is the gold standard technique with greatest sensitivity & specificity for diagnosis of Multiple sclerosis. Oligoclonal bands are present in 90% of patients with clinically definite Multiple Sclerosis. Ideally serum and CSF should be tested simultaneously to distinguish between production of oligoclonal bands due to peripheral gammopathy from that due to local production in the CNS. Other conditions which show oligoclonal bands are Subacute sclerosing panencephalitis, Inflammatory polyneuropathy, CNS Lupus and Brain tumors.

PreTest Information

No special preparation required

Detail Description

OLIGOCLONAL BANDS IgG CSF Test Cost INR:6000 Symptoms Diagnosis

OLIGOCLONAL BANDS IgG CSF Test is a diagnostic test conducted to detect any abnormality in the cerebrospinal fluid (CSF) of a patient. This test helps in identifying the presence of oligoclonal bands (OCBs) in the CSF, which are indicative of multiple sclerosis (MS) or other neurological disorders.

What are Oligoclonal Bands (OCBs)?

OCBs are a group of identical or similar antibodies that are produced by the immune system in response to a specific antigen. These bands are formed when the immune system attacks the myelin sheath, a protective covering that surrounds the nerve fibers in the brain and spinal cord. The presence of OCBs in the CSF is a strong indicator of MS or other neurological disorders.

Symptoms of Multiple Sclerosis

MS is a chronic autoimmune disease that affects the central nervous system (CNS). It is characterized by the destruction of the myelin sheath, which leads to the disruption of the communication between the brain and the rest of the body. The symptoms of MS include:

• Blurred vision or double vision
• Numbness or tingling in the limbs
• Weakness or fatigue
• Poor coordination or balance
• Problems with memory or concentration
• Difficulty speaking or swallowing

Diagnosis of Multiple Sclerosis

The diagnosis of MS is based on the patient's medical history, physical examination, and the results of various diagnostic tests. The OCBs IgG CSF Test is one of the tests used to diagnose MS. This test is performed by analyzing the CSF sample obtained from a lumbar puncture (spinal tap). The test measures the presence of OCBs in the CSF. The presence of OCBs in the CSF is a strong indicator of MS or other neurological disorders.

Cost of Oligoclonal Bands IgG CSF Test

The cost of the Oligoclonal Bands IgG CSF Test in India is around INR 6000. The cost may vary depending on the location and the laboratory where the test is conducted.

Conclusion

The Oligoclonal Bands IgG CSF Test is an important diagnostic test used to detect the presence of OCBs in the CSF. The presence of OCBs is a strong indicator of MS or other neurological disorders. If you experience any of the symptoms of MS, it is important to consult a neurologist and get the necessary tests done to diagnose the condition. The cost of the Oligoclonal Bands IgG CSF Test may vary depending on the location and the laboratory where the test is conducted.

Isoelectric focusing is the gold standard technique with greatest sensitivity & specificity for diagnosis of Multiple sclerosis. Oligoclonal bands are present in 90% of patients with clinically definite Multiple Sclerosis. Ideally serum and CSF should be tested simultaneously to distinguish between production of oligoclonal bands due to peripheral gammopathy from that due to local production in the CNS. Other conditions which show oligoclonal bands are Subacute sclerosing panencephalitis, Inflammatory polyneuropathy, CNS Lupus and Brain tumors.