Short Description

Alzheimer's disease (AD) is a degenerative disease of the brain that causes dementia, gradual loss of memory, judgment and ability to function. This generally appears in people older than age 65, but less common forms of the disease appear earlier in adulthood. Most cases of early-onset Alzheimer's disease are caused by gene mutations that can be passed from parent to child. It has been found the disorder can result from mutations in one of three genes: APP, PSEN1, or PSEN2. Another gene APOE has also been associated as a risk factor for the disorder & is a major genetic risk for AD. Presence of 1 allele of this gene increases the risk 2 to 3 fold whereas presence of 2 alleles increases the risk 16 fold in both sexes. Any mutations of these genes leads to accumulation of large amounts of a toxic protein fragment, amyloid beta peptide in the brain forming clumps called amyloid plaques, which are characteristic of Alzheimer's disease.

PreTest Information

Duly filled Whole Exome Sequencing Consent Form (Form 37) is mandatory.

Detail Description

Nx GEN SEQUENCING: ALZHEIMER'S DISEASE Test cost INR:23400 symptoms diagnosis

Alzheimer's disease is a progressive and irreversible brain disorder that affects memory, thinking, and behavior. It is the most common cause of dementia in older adults, with an estimated 5 million people in India living with the disease. Early diagnosis is crucial for effective treatment, and Nx GEN sequencing is a powerful tool that can help diagnose Alzheimer's disease.

Symptoms of Alzheimer's Disease

Alzheimer's disease is a complex condition, and symptoms can vary from person to person. However, some common symptoms of Alzheimer's disease include:

• Memory loss
• Difficulty in completing familiar tasks
• Confusion with time or place
• Trouble with language and communication
• Poor judgment
• Mood and personality changes
• Withdrawal from social activities

Diagnosing Alzheimer's Disease

Diagnosing Alzheimer's disease can be challenging, as there is no single test that can definitively diagnose the condition. Instead, doctors use a combination of physical exams, cognitive tests, and medical history to make a diagnosis. Nx GEN sequencing is a powerful tool that can help diagnose Alzheimer's disease by analyzing a patient's DNA.

Nx GEN Sequencing

Nx GEN sequencing is a cutting-edge technology that can analyze a patient's DNA to identify genetic variations that may be associated with Alzheimer's disease. The test involves sequencing the patient's DNA and comparing it to a reference genome to identify any genetic variations. This can help doctors identify genetic mutations that may be associated with Alzheimer's disease, allowing for early diagnosis and treatment.

Cost of Nx GEN Sequencing for Alzheimer's Disease

The cost of Nx GEN sequencing for Alzheimer's disease varies depending on the provider. At DNA Labs India, we offer Nx GEN sequencing for Alzheimer's disease at a cost of INR 23400. This includes sequencing and analysis of the patient's DNA, as well as a comprehensive report detailing any genetic variations that may be associated with Alzheimer's disease.

Benefits of Nx GEN Sequencing for Alzheimer's Disease

Nx GEN sequencing offers several benefits for diagnosing Alzheimer's disease, including:

• Early diagnosis: Nx GEN sequencing can identify genetic variations that may be associated with Alzheimer's disease, allowing for early diagnosis and treatment.
• Precision medicine: Nx GEN sequencing can help doctors identify specific genetic mutations that may be associated with Alzheimer's disease, allowing for more personalized and effective treatment.
• Cost-effective: Nx GEN sequencing is a cost-effective way to diagnose Alzheimer's disease, as it can help doctors identify genetic mutations with a high degree of accuracy.

Conclusion

Alzheimer's disease is a complex condition that can be challenging to diagnose. Nx GEN sequencing is a powerful tool that can help diagnose Alzheimer's disease by analyzing a patient's DNA for genetic mutations. At DNA Labs India, we offer Nx GEN sequencing for Alzheimer's disease at a cost of INR 23400. Early diagnosis is crucial for effective treatment, and Nx GEN sequencing can help doctors provide personalized and effective treatment for patients with Alzheimer's disease.

For more information about Nx GEN sequencing for Alzheimer's disease, please contact DNA Labs India.

Alzheimer's disease (AD) is a degenerative disease of the brain that causes dementia, gradual loss of memory, judgment and ability to function. This generally appears in people older than age 65, but less common forms of the disease appear earlier in adulthood. Most cases of early-onset Alzheimer's disease are caused by gene mutations that can be passed from parent to child. It has been found the disorder can result from mutations in one of three genes: APP, PSEN1, or PSEN2. Another gene APOE has also been associated as a risk factor for the disorder & is a major genetic risk for AD. Presence of 1 allele of this gene increases the risk 2 to 3 fold whereas presence of 2 alleles increases the risk 16 fold in both sexes. Any mutations of these genes leads to accumulation of large amounts of a toxic protein fragment, amyloid beta peptide in the brain forming clumps called amyloid plaques, which are characteristic of Alzheimer's disease.