Short Description

NGS genetic DNA test detecets for variant and mutation detection in NOTCH3 gene for CADASIL

PreTest Information

Clinical History of Patient who is going for NOTCH3 Gene CADASIL NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with NOTCH3 Gene CADASIL NGS Genetic DNA Test gene NOTCH3

Detail Description

What is CADASIL?

Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) is a genetic disorder that affects the blood vessels in the brain. It is caused by mutations in the NOTCH3 gene, which codes for a protein that is important for the development and maintenance of blood vessels.

What are the symptoms of CADASIL?

The symptoms of CADASIL can vary greatly from person to person, but they usually start in adulthood and get worse over time. Some of the most common symptoms include:

• Headaches
• Migraines
• Stroke-like symptoms, such as weakness or numbness on one side of the body
• Dementia
• Depression

In some cases, people with CADASIL may also experience seizures, vision problems, or difficulty with balance and coordination.

How is CADASIL diagnosed?

CADASIL is diagnosed using a combination of clinical evaluation, imaging studies, and genetic testing. A doctor may order an MRI or CT scan to look for signs of damage in the brain's white matter. Genetic testing can confirm the presence of NOTCH3 gene mutations.

What is NGS Genetic DNA Testing?

Next-generation sequencing (NGS) is a powerful technology that can analyze large amounts of genetic data quickly and accurately. NGS genetic DNA testing can be used to diagnose a wide range of genetic disorders, including CADASIL.

How much does the NGS Genetic DNA Test for CADASIL cost in India?

The cost of NGS Genetic DNA Testing for CADASIL in India is approximately INR 20,000. However, the cost may vary depending on the testing facility and other factors.

Conclusion

CADASIL is a serious genetic disorder that can cause a wide range of symptoms, including headaches, migraines, and dementia. NGS Genetic DNA Testing can be used to diagnose CADASIL quickly and accurately. If you or a loved one is experiencing symptoms of CADASIL, it is important to speak with a doctor and consider genetic testing.

At DNA Labs India, we offer NGS Genetic DNA Testing for CADASIL and other genetic disorders. Our team of experts is dedicated to providing accurate and timely diagnoses to help patients get the treatment they need. Contact us today to learn more.