Short Description

NGS genetic DNA test detecets for variant and mutation detection in NKX2-2 gene for Maturity-onset diabetes of the young, NKX2-2 related

PreTest Information

Clinical History of Patient who is going for NKX2-2 Gene Maturity-onset diabetes of the young, NKX2-2 related NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Maturity-onset diabetes of the young, NKX2-2 related

Detail Description

NKX2-2 Gene and Maturity-Onset Diabetes of the Young

Maturity-Onset Diabetes of the Young (MODY) is a rare, genetic form of diabetes that affects young people and is caused by a mutation in one of several genes. One of these genes is the NKX2-2 gene. Mutations in this gene can cause MODY type 7, which is characterized by impaired glucose regulation and insulin secretion.

What is the NKX2-2 gene?

The NKX2-2 gene is located on chromosome 20 and encodes a protein called NKX2-2. This protein is a transcription factor, which means it regulates the expression of other genes. In particular, NKX2-2 is important for the development and function of the pancreas, which produces insulin to regulate blood sugar levels.

Symptoms of NKX2-2 related MODY

The symptoms of NKX2-2 related MODY are similar to those of other forms of diabetes, including:

• Increased thirst
• Increased urination
• Tiredness
• Blurred vision
• Slow healing of cuts and wounds

However, because MODY is a genetic form of diabetes, it often affects younger people and may not require insulin therapy.

Diagnosis of NKX2-2 related MODY

Diagnosis of MODY can be difficult because it is a rare form of diabetes and is often misdiagnosed as type 1 or type 2 diabetes. However, genetic testing can identify mutations in the NKX2-2 gene and confirm a diagnosis of MODY type 7.

NGS Genetic DNA Test for NKX2-2 related MODY

The NGS Genetic DNA Test is a comprehensive genetic test that can identify mutations in the NKX2-2 gene and other genes associated with MODY. This test uses next-generation sequencing (NGS) technology to analyze the entire DNA sequence of the genes in question, allowing for a more accurate diagnosis.

Cost of NGS Genetic DNA Test for NKX2-2 related MODY

The cost of the NGS Genetic DNA Test for NKX2-2 related MODY is INR 20,000. This test is available at DNA Labs India, a leading provider of genetic testing services in India.

Conclusion

MODY is a rare form of diabetes caused by mutations in specific genes, including the NKX2-2 gene. Symptoms of NKX2-2 related MODY are similar to those of other forms of diabetes, but genetic testing is required for an accurate diagnosis. The NGS Genetic DNA Test is a comprehensive genetic test that can identify mutations in the NKX2-2 gene and other genes associated with MODY. DNA Labs India offers this test at a cost of INR 20,000.

If you suspect that you or a loved one may have MODY, it is important to seek medical advice and consider genetic testing to ensure an accurate diagnosis and appropriate treatment.

For more information about genetic testing services at DNA Labs India, please visit our website.