Short Description

NGS genetic DNA test detecets for variant and mutation detection in NCF4 gene for Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 3

PreTest Information

Clinical History of Patient who is going for NCF4 Gene Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 3 NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with NCF4 Gene Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 3 NGS Genetic DNA Test gene NCF4

Detail Description

DNA Labs India: NCF4 Gene Granulomatous Disease – Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Granulomatous disease is a rare condition that affects the immune system, causing the formation of granulomas or small lumps of cells in different parts of the body. Granulomatous disease can be chronic and may lead to severe complications. One type of granulomatous disease is caused by mutations in the NCF4 gene.

NCF4 Gene Granulomatous Disease

NCF4 gene granulomatous disease is an autosomal recessive disease that is caused by mutations in the NCF4 gene. This gene provides instructions for making a protein that is involved in the immune system's response to infections. The protein produced by the NCF4 gene is a subunit of the NADPH oxidase enzyme complex, which helps in killing bacteria and other pathogens.

In individuals with NCF4 gene mutations, the NADPH oxidase enzyme complex is not formed correctly, leading to impaired immune system function. This impairment can cause the formation of granulomas in different parts of the body, leading to symptoms such as:

• Fever
• Coughing
• Shortness of breath
• Persistent infections
• Skin rashes

NCF4 gene granulomatous disease is also known as cytochrome b-positive, type 3 granulomatous disease.

Diagnosis

NCF4 gene granulomatous disease is diagnosed through genetic testing. Next-generation sequencing (NGS) genetic testing is a type of genetic testing that can analyze multiple genes simultaneously, allowing for a more comprehensive diagnosis. NGS genetic testing can detect mutations in the NCF4 gene and other genes associated with granulomatous disease.

Other diagnostic tests that may be performed include blood tests, imaging tests, and biopsy.

NGS Genetic DNA Test Cost

The cost of NGS genetic DNA testing for NCF4 gene granulomatous disease in India is approximately INR 20,000. The cost may vary depending on the specific laboratory and testing method used.

Conclusion

NCF4 gene granulomatous disease is a rare condition that can cause significant complications. Genetic testing, including NGS genetic DNA testing, can help diagnose the condition and guide treatment options. If you or a loved one is experiencing symptoms of granulomatous disease, it is important to consult with a healthcare professional to determine the underlying cause and appropriate treatment plan.

Contact DNA Labs India for more information on NCF4 gene granulomatous disease and genetic testing options.