Short Description

Myelin associated glycoprotein (MAG) and sulphated glucuronyl paragloboside (SGPG) antibodies are present in a subgroup of sensory demyelinating neuropathies. Axonal neuropathies can present with only monoclonal IgM anti-SGPG activity. Presence of anti-SGPG antibodies alone is more characteristic of axonal non-demyelinating neuropathy. There is a relationship between the titer of anti-MAG antibodies and the degree of demyelination.

PreTest Information

Overnight fasting is preferred. Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Detail Description

MYELIN ASSOCIATED GLYCOPROTEIN- SULFATED GLUCURONIC PARAGLOBOSIDE AUTOANTIBODY (MAG-SGPG) IgM Test

DNA Labs India offers the Myelin Associated Glycoprotein-Sulfated Glucuronic Paragloboside Autoantibody (MAG-SGPG) IgM Test at a cost of INR 14,000. This test helps in diagnosing certain neurological conditions that affect the peripheral nerves.

Symptoms

The symptoms of conditions that can be diagnosed using the MAG-SGPG IgM Test include:

• Weakness or numbness in the arms or legs
• Tingling or burning sensation in the arms or legs
• Difficulty in walking or moving
• Loss of reflexes
• Fatigue
• Pain

Diagnosis

The MAG-SGPG IgM Test is used to diagnose certain neurological conditions that affect the peripheral nerves, such as:

• Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
• Monoclonal Gammopathy of Undetermined Significance (MGUS)
• Waldenström's Macroglobulinemia
• Multiple Myeloma
• Other peripheral neuropathies

The test detects MAG-SGPG IgM antibodies in the blood. These antibodies are produced by the body's immune system in response to the MAG-SGPG antigen, which is found on the surface of nerve cells. The presence of these antibodies indicates that the immune system is attacking the peripheral nerves, leading to the symptoms of the neurological condition.

Cost

The cost of the MAG-SGPG IgM Test at DNA Labs India is INR 14,000.

Conclusion

If you are experiencing any of the symptoms mentioned above, it is important to consult a doctor. The MAG-SGPG IgM Test can help in diagnosing certain neurological conditions that affect the peripheral nerves. DNA Labs India offers this test at an affordable cost of INR 14,000.

It is important to note that this blog is for informational purposes only and should not be used as a substitute for medical advice. Please consult a doctor for any medical concerns.

Myelin associated glycoprotein (MAG) and sulphated glucuronyl paragloboside (SGPG) antibodies are present in a subgroup of sensory demyelinating neuropathies. Axonal neuropathies can present with only monoclonal IgM anti-SGPG activity. Presence of anti-SGPG antibodies alone is more characteristic of axonal non-demyelinating neuropathy. There is a relationship between the titer of anti-MAG antibodies and the degree of demyelination.