Short Description

NGS genetic DNA test detecets for variant and mutation detection in MXRA5 gene for Autism spectrum, MXRA5 related

PreTest Information

Clinical History of Patient who is going for MXRA5 Gene Autism spectrum, MXRA5 related NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MXRA5 Gene Autism spectrum, MXRA5 related

Detail Description

MXRA5 Gene and Autism Spectrum Disorder: Symptoms, Diagnosis, and NGS Genetic DNA Test Cost

Autism Spectrum Disorder (ASD) is a complex neurodevelopmental disorder that affects communication, social interaction, and behavior. It is estimated that 1 in 54 children in the United States has ASD, and the prevalence is increasing globally. While the exact causes of ASD are unknown, research has identified various genetic and environmental risk factors that may contribute to its development.

One gene that has been implicated in the development of ASD is the MXRA5 gene. MXRA5 is a protein-coding gene that is located on chromosome 1. It is involved in various cellular processes, including cell adhesion and migration, and has been shown to be dysregulated in individuals with ASD.

Symptoms of ASD

The symptoms of ASD can vary widely, but generally, individuals with ASD have difficulty with social communication and interaction, repetitive behaviors, and sensory sensitivities. Some common symptoms of ASD include:

• Difficulty with social interactions, including making eye contact, initiating and maintaining conversations, and understanding nonverbal cues
• Repetitive behaviors, such as rocking, spinning, or hand flapping
• Difficulty with changes in routine or environment
• Sensory sensitivities, such as being overly sensitive to certain sounds, textures, or smells

Diagnosis of ASD

Diagnosing ASD can be challenging, as there is no specific medical test or imaging study that can definitively diagnose the disorder. Instead, diagnosis is typically based on a comprehensive evaluation that includes:

• Observation of the individual's behavior and communication skills
• Developmental and medical history
• Standardized tests and questionnaires

MXRA5 Gene and ASD

Research has shown that mutations in the MXRA5 gene may be associated with an increased risk of developing ASD. Specifically, a study published in the journal Nature Genetics in 2016 identified rare, inherited mutations in the MXRA5 gene in individuals with ASD. The study found that these mutations disrupted the normal function of the MXRA5 protein, leading to abnormalities in brain development and function.

NGS Genetic DNA Test for MXRA5 Gene

Advances in genetic testing technology have made it possible to identify mutations in the MXRA5 gene using next-generation sequencing (NGS) techniques. NGS is a high-throughput DNA sequencing method that allows for the rapid and cost-effective analysis of large amounts of DNA.

The cost of an NGS genetic DNA test for the MXRA5 gene in India is approximately INR 20,000. This test involves sequencing the entire MXRA5 gene to identify any mutations that may be present. Results of the test can help to confirm a diagnosis of ASD and provide valuable information for genetic counseling and family planning.

Conclusion

The MXRA5 gene is one of many genes that may contribute to the development of ASD. While there is still much to be learned about the underlying causes of ASD, advances in genetic testing technology are providing new insights into the genetic basis of the disorder. If you or a loved one is experiencing symptoms of ASD, it is important to seek a comprehensive evaluation from a qualified healthcare professional.

At DNA Labs India, we offer a range of genetic testing services, including NGS genetic DNA testing for the MXRA5 gene. Our state-of-the-art laboratory and experienced team of geneticists and genetic counselors are dedicated to providing accurate, reliable, and personalized testing services to individuals and families across India.

Contact us today to learn more about our genetic testing services and how we can help you get the answers you need.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MXRA5 Gene Autism spectrum, MXRA5 related NGS Genetic DNA Test