Short Description

NGS genetic DNA test detecets for variant and mutation detection in MVK gene for Porokeratosis type 3, disseminated superficial actinic

PreTest Information

Clinical History of Patient who is going for MVK Gene Porokeratosis type 3, disseminated superficial actinic NGS Genetic DNA Test. A Genetic Counselling session to draw a pedigree chart of family members affected with MVK Gene Porokeratosis type 3, disseminated superficial actinic NGS Genetic DNA Test gene MVK

Detail Description

DNA Labs India: MVK Gene Porokeratosis Type 3 Disseminated Superficial Actinic NGS Genetic DNA Test

Porokeratosis is a rare skin disorder that is characterized by the formation of keratotic lesions on the skin. Porokeratosis type 3, disseminated superficial actinic (DSAP), is a subtype of porokeratosis that is associated with mutations in the MVK gene. DNA Labs India offers an NGS genetic DNA test for MVK Gene Porokeratosis Type 3, DSAP at a cost of INR 20,000.

Symptoms

DSAP usually appears during the third or fourth decade of life and is more common in women. The lesions are typically small, flat, and have a ring-like appearance with a slightly elevated border. They are most commonly found on the forearms, hands, and legs, but can also occur on the face and trunk. The lesions are usually asymptomatic but can occasionally be itchy or tender.

Diagnosis

DSAP is usually diagnosed based on clinical examination and skin biopsy. The biopsy will show characteristic features of the disorder, such as a cornoid lamella, which is a thin column of keratin that extends from the epidermis into the dermis. Genetic testing can confirm the diagnosis and identify the specific MVK gene mutation responsible for the disorder.

NGS Genetic DNA Test

DNA Labs India offers an NGS genetic DNA test for MVK Gene Porokeratosis Type 3, DSAP at a cost of INR 20,000. The test uses next-generation sequencing (NGS) technology to analyze the entire MVK gene and identify any mutations that may be present. The test is non-invasive and requires only a small sample of blood or saliva.

Benefits of Genetic Testing

Genetic testing can provide several benefits for individuals with DSAP. First, it can confirm the diagnosis and provide a better understanding of the disorder. Second, it can identify the specific MVK gene mutation responsible for the disorder, which can help with genetic counseling and family planning. Third, it can help guide treatment decisions, as some treatments may be more effective for certain mutations.

Conclusion

DSAP is a rare subtype of porokeratosis that is associated with mutations in the MVK gene. DNA Labs India offers an NGS genetic DNA test for MVK Gene Porokeratosis Type 3, DSAP at a cost of INR 20,000. Genetic testing can provide several benefits for individuals with DSAP, including a confirmed diagnosis, identification of the specific MVK gene mutation, and guidance for treatment decisions.

For more information or to schedule a test, contact DNA Labs India today.