Short Description

MuSK antibodies have been detected in patients with Myasthenia gravis who are seronegative for Acetylcholine receptor (AChR) antibodies. Antibodies to MuSK are present in 40% of AChR antibody negative patients. This assay is used to evaluate patient response to therapies for ongoing management.

PreTest Information

No special preparation required

Detail Description

MuSK (MUSCLE SPECIFIC KINASE) ANTIBODY Test cost INR:8000 symptoms diagnosis

Myasthenia Gravis (MG) is a chronic autoimmune disorder that affects the neuromuscular junction, which is responsible for the transmission of impulses from the nerve to the muscle. The disorder occurs due to the production of autoantibodies that attack the receptors present on the neuromuscular junction, causing muscle weakness and fatigue.

Muscle-specific kinase (MuSK) is a protein that is present on the neuromuscular junction. In about 40-50% of MG patients, autoantibodies are produced against MuSK instead of the acetylcholine receptor (AChR). This type of MG is known as MuSK-MG and is more common in women than men.

Symptoms of MuSK-MG

The symptoms of MuSK-MG are similar to those of AChR-MG and include:

• Muscle weakness in the arms, legs, neck, and face
• Fatigue
• Drooping eyelids
• Double vision
• Difficulty in swallowing and breathing

Diagnosis of MuSK-MG

The diagnosis of MuSK-MG involves a combination of clinical evaluation, blood tests, and imaging studies. The following tests may be recommended:

• Physical examination to check for muscle weakness and other symptoms
• Blood tests to detect the presence of MuSK antibodies
• Electromyography (EMG) to measure the electrical activity in the muscles
• Magnetic resonance imaging (MRI) to check for any abnormalities in the muscles and nerves

MuSK (MUSCLE SPECIFIC KINASE) ANTIBODY Test cost INR:8000

The MuSK antibody test is a blood test that detects the presence of MuSK antibodies in the blood. The test is used to diagnose MuSK-MG and is usually performed along with other tests such as EMG and MRI. The cost of the MuSK antibody test in India is around INR 8000.

Conclusion

MuSK-MG is a type of autoimmune disorder that affects the neuromuscular junction. The disorder is diagnosed through a combination of clinical evaluation, blood tests, and imaging studies. The MuSK antibody test is a blood test that detects the presence of MuSK antibodies in the blood and is used to diagnose MuSK-MG. The cost of the MuSK antibody test in India is around INR 8000. If you experience any symptoms of MuSK-MG, it is important to consult a doctor for a proper diagnosis and treatment.

For more information on MuSK (MUSCLE SPECIFIC KINASE) ANTIBODY Test, please visit DNA Labs India website.