Short Description

NGS genetic DNA test detecets for variant and mutation detection in MT-ND5 gene for Mitochondrial complex I deficiency

PreTest Information

Clinical History of Patient who is going for MT-ND5 Gene Mitochondrial complex I deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MT-ND5 Gene Mitochondrial complex I deficiency

Detail Description

MT-ND5 Gene Mitochondrial Complex I Deficiency NGS Genetic DNA Test

MT-ND5 gene mitochondrial complex I deficiency is a rare genetic disorder that affects the mitochondrial respiratory chain. The respiratory chain is responsible for producing ATP, which is the main source of energy for the body. Mitochondrial complex I deficiency is caused by mutations in the MT-ND5 gene, which encodes a subunit of the respiratory chain complex. This deficiency can lead to a wide range of symptoms, including developmental delays, muscle weakness, and organ dysfunction.

Symptoms of MT-ND5 Gene Mitochondrial Complex I Deficiency

The symptoms of MT-ND5 gene mitochondrial complex I deficiency can vary widely depending on the severity of the deficiency. Some common symptoms include:

• Developmental delays, including delays in walking and talking
• Muscle weakness and poor muscle tone
• Organ dysfunction, including liver and kidney dysfunction
• Seizures
• Vision and hearing problems
• Heart problems, including cardiac arrhythmias and heart failure

Diagnosis of MT-ND5 Gene Mitochondrial Complex I Deficiency

MT-ND5 gene mitochondrial complex I deficiency can be diagnosed through genetic testing, specifically through next-generation sequencing (NGS) of the MT-ND5 gene. NGS is a powerful tool that allows for the simultaneous analysis of multiple genes. This test can identify mutations in the MT-ND5 gene that are associated with mitochondrial complex I deficiency.

Cost of NGS Genetic DNA Test for MT-ND5 Gene Mitochondrial Complex I Deficiency

The cost of NGS genetic DNA testing for MT-ND5 gene mitochondrial complex I deficiency can vary depending on the laboratory and the specific test being performed. At DNA Labs India, the cost of this test is INR 20,000.

Conclusion

MT-ND5 gene mitochondrial complex I deficiency is a rare genetic disorder that can cause a wide range of symptoms. NGS genetic DNA testing can be used to diagnose this condition, and the cost of this test at DNA Labs India is INR 20,000. If you or a loved one is experiencing symptoms of mitochondrial complex I deficiency, talk to your doctor about the possibility of genetic testing.

For more information about genetic testing and other DNA-related services, visit DNA Labs India's website.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MT-ND5 Gene Mitochondrial complex I deficiency NGS Genetic DNA Test