Short Description

NGS genetic DNA test detecets for variant and mutation detection in MT-ND5 gene for Leigh syndrome due to mitochondrial complex I deficiency

PreTest Information

Clinical History of Patient who is going for MT-ND5 Gene Leigh syndrome due to mitochondrial complex I deficiency NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MT-ND5 Gene Leigh syndrome due to mitochondrial complex I deficiency

Detail Description

MT-ND5 Gene Leigh Syndrome Due to Mitochondrial Complex I Deficiency NGS Genetic DNA Test Cost INR: 20000 Symptoms Diagnosis

Leigh syndrome is a rare, inherited neurological disorder that affects the central nervous system. It is caused by mutations in the MT-ND5 gene, which is responsible for encoding a subunit of mitochondrial complex I. Mitochondrial complex I is a protein complex that plays a vital role in the production of energy in the cells of the body. Mutations in the MT-ND5 gene result in mitochondrial complex I deficiency, which leads to a buildup of lactic acid in the body and the death of brain cells.

The symptoms of Leigh syndrome due to mitochondrial complex I deficiency can vary widely, but typically include developmental delays, muscle weakness, and difficulty coordinating movements. Other symptoms may include seizures, respiratory problems, and vision and hearing loss.

Diagnosis

Diagnosis of Leigh syndrome due to mitochondrial complex I deficiency can be difficult, as the symptoms can be similar to those of other neurological disorders. However, genetic testing can help confirm a diagnosis. NGS (Next-Generation Sequencing) Genetic DNA testing is a highly accurate and effective way to identify mutations in the MT-ND5 gene. This type of testing can analyze multiple genes at once, making it a useful tool for identifying mutations in patients with complex disorders.

Cost

The cost of the NGS Genetic DNA test for Leigh syndrome due to mitochondrial complex I deficiency can vary depending on the laboratory performing the test. At DNA Labs India, the cost of this test is INR 20,000.

Conclusion

Leigh syndrome due to mitochondrial complex I deficiency is a rare but serious neurological disorder that can be difficult to diagnose. Genetic testing, such as NGS Genetic DNA testing, can help confirm a diagnosis and provide important information for treatment and management of the condition. If you or a loved one are experiencing symptoms of Leigh syndrome, speak to your healthcare provider about the possibility of genetic testing.

At DNA Labs India, we offer a wide range of genetic testing services, including NGS Genetic DNA testing for Leigh syndrome due to mitochondrial complex I deficiency. Contact us today to learn more about our services and how we can help you.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MT-ND5 Gene Leigh syndrome due to mitochondrial complex I deficiency NGS Genetic DNA Test