Short Description

NGS genetic DNA test detecets for variant and mutation detection in MPZ gene for Dejerine-Sottas disease

PreTest Information

Clinical History of Patient who is going for MPZ Gene Dejerine-Sottas disease NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with MPZ Gene Dejerine-Sottas disease

Detail Description

MPZ Gene Dejerine-Sottas Disease NGS Genetic DNA Test

Dejerine-Sottas Disease (DSD) is a rare genetic disorder that affects the peripheral nerves. It is also known as hereditary motor and sensory neuropathy type III (HMSN III) or Charcot-Marie-Tooth disease type 3 (CMT3). DSD is caused by mutations in the myelin protein zero (MPZ) gene. The MPZ gene provides instructions for making a protein called myelin protein zero, which is essential for the formation and maintenance of myelin, a fatty substance that covers and protects nerve fibers.

NGS Genetic DNA Test is a diagnostic test that uses next-generation sequencing technology to analyze the MPZ gene. This test can identify mutations in the MPZ gene that cause DSD. The NGS Genetic DNA Test is a non-invasive and highly accurate test that can provide a definitive diagnosis of DSD.

Symptoms of Dejerine-Sottas Disease

The symptoms of Dejerine-Sottas Disease vary from person to person. The most common symptoms include:

• Progressive muscle weakness
• Numbness and tingling in the hands and feet
• Loss of sensation
• Difficulty walking
• Foot deformities
• High foot arches
• Scoliosis

Diagnosis of Dejerine-Sottas Disease

Diagnosis of Dejerine-Sottas Disease is based on clinical symptoms, family history, and genetic testing. NGS Genetic DNA Test is the most accurate and reliable test for diagnosing DSD. The test can identify mutations in the MPZ gene that cause DSD. The test can also be used for carrier testing for family members of affected individuals.

Cost of NGS Genetic DNA Test for Dejerine-Sottas Disease

The cost of NGS Genetic DNA Test for Dejerine-Sottas Disease at DNA Labs India is INR 20,000. The test is highly accurate and provides a definitive diagnosis of DSD. The test is non-invasive and can be performed on a blood or saliva sample.

Conclusion

Dejerine-Sottas Disease is a rare genetic disorder that affects the peripheral nerves. NGS Genetic DNA Test is a highly accurate and reliable test for diagnosing DSD. The test can identify mutations in the MPZ gene that cause DSD. The cost of NGS Genetic DNA Test for Dejerine-Sottas Disease at DNA Labs India is INR 20,000. If you or your family member is experiencing symptoms of DSD, it is recommended to undergo genetic testing for a definitive diagnosis.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MPZ Gene Dejerine-Sottas disease NGS Genetic DNA Test