Short Description

Mutations in exon 10 of MPL have been detected in approximately 5% of patients with Primary myelofibrosis (PMF) and Essential thrombocythemia (ET).

PreTest Information

Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.

Detail Description

MPL (MYELOPROLIFERATIVE LEUKEMIA) GENE MUTATION Test cost INR:6500 symptoms diagnosis

MPL gene mutation is a genetic condition that affects the blood cells and can lead to various complications. The MPL gene is responsible for producing a protein called thrombopoietin receptor, which plays a crucial role in the production of platelets. In MPL gene mutation, the gene produces an abnormal protein, which can lead to the overproduction of blood cells, and in some cases, to the development of leukemia.

Symptoms of MPL gene mutation

The symptoms of MPL gene mutation can vary from person to person and can also depend on the severity of the condition. Some common symptoms include:

• Fatigue and weakness
• Shortness of breath
• Pale skin
• Easy bruising and bleeding
• Enlarged spleen and liver
• Joint pain

Diagnosis of MPL gene mutation

The diagnosis of MPL gene mutation involves a series of tests that can help identify the abnormality in the MPL gene. Some of these tests include:

• Blood tests to check for the levels of blood cells and platelets
• Bone marrow biopsy to examine the bone marrow cells
• Genetic testing to detect the mutation in the MPL gene

MPL gene mutation test cost

The cost of the MPL gene mutation test can vary depending on the location and the laboratory where the test is performed. In India, the cost of the test is typically around INR 6500.

Conclusion

The MPL gene mutation is a genetic condition that can lead to various complications, including the development of leukemia. Early diagnosis and treatment can help manage the symptoms and improve the quality of life of the affected individuals. If you are experiencing any of the symptoms mentioned above, it is advisable to consult a doctor and get a proper diagnosis.

At DNA Labs India, we offer a comprehensive range of genetic testing services, including the MPL gene mutation test, at an affordable cost. Our experienced team of professionals uses the latest technology and techniques to ensure accurate and reliable results. Contact us today to learn more about our services.