MITOCHONDRIAL ANTIBODY (AMA) IFA Test is a blood test that helps diagnose autoimmune liver diseases such as Primary Biliary Cholangitis (PBC) and Autoimmune Hepatitis (AIH). The test detects the presence of autoantibodies against mitochondria, which are organelles that produce energy in cells.
The AMA test is performed using the Indirect Immunofluorescence Assay (IFA) method, which involves exposing the patient's blood sample to a substrate containing mitochondrial antigens. If AMA is present in the blood sample, it will bind to the mitochondrial antigens, which can be visualized under a microscope using a fluorescent dye.
Symptoms of Autoimmune Liver Diseases
Autoimmune liver diseases can have various symptoms, including:
- Fatigue
- Abdominal pain and discomfort
- Jaundice
- Itching
- Dark urine
- Pale stools
- Loss of appetite
- Nausea and vomiting
- Weight loss
Diagnosis of Autoimmune Liver Diseases
Diagnosis of autoimmune liver diseases involves several tests, including:
- AMA Test
- Liver Function Tests (LFTs)
- Immunoglobulin Tests
- Liver Biopsy
The AMA test is a crucial diagnostic tool for autoimmune liver diseases as it has a high specificity and sensitivity. A positive AMA test result indicates the presence of autoantibodies against mitochondria, which are commonly found in patients with PBC and AIH.
AMA IFA Test Cost
The cost of the AMA IFA Test in India is INR 1989. DNA Labs India offers the most accurate and reliable test results at an affordable price. We use the latest technology and equipment to ensure the highest quality of testing.
If you are experiencing symptoms of autoimmune liver diseases, it is essential to get tested as early as possible. Early diagnosis and treatment can help prevent further damage to the liver and improve the patient's quality of life.
Mitochondrial antibody is present in approximately > 90% patients with Primary Biliary Cirrhosis. This assay is not useful for indicating the prognosis of the disease or monitoring the course of the disease.